Literature DB >> 7620630

Laufband therapy based on 'rules of spinal locomotion' is effective in spinal cord injured persons.

A Wernig1, S Müller, A Nanassy, E Cagol.   

Abstract

Rehabilitation of locomotion in spinal cord (s.c.) injured patients is unsatisfactory. Here we report the effects of a novel 'Laufband (LB; treadmill) therapy' based on 'rules of spinal locomotion' derived from lower vertebrates. Eighty-nine incompletely paralysed (44 chronic and 45 acute) para- and tetraplegics underwent this therapy, then were compared with 64 patients (24 chronic and 40 acute) treated conventionally. The programme consisted of daily upright walking on a motor driven LB initially with body weight support (BWS) provided by a harness and assisted limb movements by the therapists when necessary. Forty-four chronic patients with different degrees of paralysis undertook the programme for 3-20 weeks (median = 10.5), 0.5-18 years after s.c. damage. At the onset of LB therapy 33/44 patients were wheelchair-bound (no standing and/or walking without help by others) whereas at the end of therapy 25 patients (76%) had learned to walk independently, 7 patients with help [corrected]. Only 1 subject did not improve. It was striking that voluntary muscle activity in the resting position was still low in several patients who had gained walking capability. Eleven patients who could already walk before LB therapy improved in speed and endurance. Of the 44 patients, six were capable of staircase walking before LB therapy compared with 34 afterwards. In order to validate the apparent superiority of LB therapy two types of comparisons were performed. In a 'temporal' control 12 spastic paretic patients, still wheelchair-bound after the period of postacute conventional therapy, performed LB immediately thereafter. After completion of LB therapy nine of these patients had learned to walk without help from others.(ABSTRACT TRUNCATED AT 250 WORDS)

Entities:  

Mesh:

Year:  1995        PMID: 7620630     DOI: 10.1111/j.1460-9568.1995.tb00686.x

Source DB:  PubMed          Journal:  Eur J Neurosci        ISSN: 0953-816X            Impact factor:   3.386


  74 in total

Review 1.  Could enhanced reflex function contribute to improving locomotion after spinal cord repair?

Authors:  K G Pearson
Journal:  J Physiol       Date:  2001-05-15       Impact factor: 5.182

Review 2.  Retraining the injured spinal cord.

Authors:  V R Edgerton; R D Leon; S J Harkema; J A Hodgson; N London; D J Reinkensmeyer; R R Roy; R J Talmadge; N J Tillakaratne; W Timoszyk; A Tobin
Journal:  J Physiol       Date:  2001-05-15       Impact factor: 5.182

3.  Spinal cats on the treadmill: changes in load pathways.

Authors:  Marie-Pascale Côté; Ariane Ménard; Jean-Pierre Gossard
Journal:  J Neurosci       Date:  2003-04-01       Impact factor: 6.167

4.  Interventions to Reduce Spasticity and Improve Function in People With Chronic Incomplete Spinal Cord Injury: Distinctions Revealed by Different Analytical Methods.

Authors:  Lynsey D Duffell; Geoffrey L Brown; Mehdi M Mirbagheri
Journal:  Neurorehabil Neural Repair       Date:  2014-11-14       Impact factor: 3.919

5.  Volitional muscle strength in the legs predicts changes in walking speed following locomotor training in people with chronic spinal cord injury.

Authors:  Jaynie F Yang; Jonathan Norton; Jennifer Nevett-Duchcherer; Francois D Roy; Douglas P Gross; Monica A Gorassini
Journal:  Phys Ther       Date:  2011-04-21

6.  Short-term effects of functional electrical stimulation on motor-evoked potentials in ankle flexor and extensor muscles.

Authors:  Aiko Kido Thompson; Richard B Stein
Journal:  Exp Brain Res       Date:  2004-07-09       Impact factor: 1.972

7.  Induction of locomotor-like EMG activity in paraplegic persons by orthotic gait training.

Authors:  Kimitaka Nakazawa; Wataru Kakihana; Noritaka Kawashima; Masami Akai; Hideo Yano
Journal:  Exp Brain Res       Date:  2004-02-17       Impact factor: 1.972

8.  Response to 'Randomised controlled trials do not always give the results we want but that doesn't mean we should abandon randomised controlled trials'.

Authors:  A Wernig
Journal:  Spinal Cord       Date:  2015-08-18       Impact factor: 2.772

Review 9.  Training to achieve over ground walking after spinal cord injury: a review of who, what, when, and how.

Authors:  Jaynie F Yang; Kristin E Musselman
Journal:  J Spinal Cord Med       Date:  2012-09       Impact factor: 1.985

10.  Opioid regulation of spinal cord plasticity: evidence the kappa-2 opioid receptor agonist GR89696 inhibits learning within the rat spinal cord.

Authors:  Stephanie N Washburn; Marissa L Maultsby; Denise A Puga; James W Grau
Journal:  Neurobiol Learn Mem       Date:  2007-11-05       Impact factor: 2.877

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.