| Literature DB >> 19257559 |
Weichun Pan1, Luis Filobelo, Ngoc D Q Pham, Oleg Galkin, Veselina V Uzunova, Peter G Vekilov.
Abstract
We probe the transport properties in protein solutions stable with respect to any, solid or liquid, phase separation as a step in the understanding of transport in the cytosol of live cells. We determine the mean-squared displacement of probe particles in the time range 10;{-3}-10 s in solutions of a model protein. The tested solutions exhibit significant elasticity at high frequencies, while at low frequencies, they are purely viscous. We attribute this viscoelasticity to a dense network of weakly-bound chains of protein molecules with characteristic lifetime of 10-100 ms. The found intrinsic viscoelasticity of protein solutions should be considered in biochemical kinetics models.Mesh:
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Year: 2009 PMID: 19257559 DOI: 10.1103/PhysRevLett.102.058101
Source DB: PubMed Journal: Phys Rev Lett ISSN: 0031-9007 Impact factor: 9.161