BACKGROUND: Although executive functioning (EF) was found to be associated with cognitive deterioration, the majority of the tests for assessing EF lack ecological validity. AIMS: To examine the feasibility and the validity of the virtual action planning supermarket (VAP-S) for the diagnosis of patients with mild cognitive impairment (MCI). METHODS: Thirty MCI patients (mean age = 69.5 years) were compared to 30 healthy elderly persons (mean age = 69.2 years) in their performance of the VAP-S. RESULTS: Significant differences were found between the groups in the majority of the measures of the VAP-S. The combination of the MMSE and the trajectory duration provided the best predictive classification for the groups. CONCLUSION: MCI patients have EF deficits, and the VAP-S is a viable tool to assess EF deficits in patients with MCI and healthy elderly.
BACKGROUND: Although executive functioning (EF) was found to be associated with cognitive deterioration, the majority of the tests for assessing EF lack ecological validity. AIMS: To examine the feasibility and the validity of the virtual action planning supermarket (VAP-S) for the diagnosis of patients with mild cognitive impairment (MCI). METHODS: Thirty MCI patients (mean age = 69.5 years) were compared to 30 healthy elderly persons (mean age = 69.2 years) in their performance of the VAP-S. RESULTS: Significant differences were found between the groups in the majority of the measures of the VAP-S. The combination of the MMSE and the trajectory duration provided the best predictive classification for the groups. CONCLUSION: MCI patients have EF deficits, and the VAP-S is a viable tool to assess EF deficits in patients with MCI and healthy elderly.
Authors: Luisa Jurjanz; Markus Donix; Eva C Amanatidis; Shirin Meyer; Katrin Poettrich; Thomas Huebner; Damaris Baeumler; Michael N Smolka; Vjera A Holthoff Journal: PLoS One Date: 2011-05-20 Impact factor: 3.240
Authors: Katrin Jekel; Marinella Damian; Carina Wattmo; Lucrezia Hausner; Roger Bullock; Peter J Connelly; Bruno Dubois; Maria Eriksdotter; Michael Ewers; Elmar Graessel; Milica G Kramberger; Emma Law; Patrizia Mecocci; José L Molinuevo; Louise Nygård; Marcel Gm Olde-Rikkert; Jean-Marc Orgogozo; Florence Pasquier; Karine Peres; Eric Salmon; Sietske Am Sikkes; Tomasz Sobow; René Spiegel; Magda Tsolaki; Bengt Winblad; Lutz Frölich Journal: Alzheimers Res Ther Date: 2015-03-18 Impact factor: 6.982
Authors: Philip Grewe; Agnes Kohsik; David Flentge; Eugen Dyck; Mario Botsch; York Winter; Hans J Markowitsch; Christian G Bien; Martina Piefke Journal: J Neuroeng Rehabil Date: 2013-04-23 Impact factor: 4.262