OBJECTIVE: To examine the association between stressful life events and semen parameters. DESIGN: Cross-sectional analysis in a pregnancy cohort study. SETTING: Prenatal clinics in five U.S. cities. PATIENT(S): Fertile men (n = 744) in the Study for Future Families, a cohort study of pregnant women and their partners. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Sperm concentration, percent motile, and percent normal morphology and classification above/below World Health Organization (WHO) cutoffs for semen quality. RESULT(S): After adjusting for confounders, men reporting 2+ recent stressful life events had an increased risk of being classified below WHO thresholds for "normal" defined by concentration, motility, and morphology criteria compared with men reporting <2 stressful life events (odds ratio [OR] = 2.06; 95% confidence interval [CI], 1.18, 3.61; OR = 1.54; 95% CI, 1.04, 2.29; OR = 1.93; 95% CI, 1.02, 3.66 for concentration, motility and morphology, respectively). Men experiencing 2+ stressful life events had lower sperm concentration (log scale, beta = -0.25; 95% CI, -0.38, -0.11) and lower percent motile sperm (beta = -1.95; 95% CI, -3.98, 0.07), but percent normal morphology was less affected. CONCLUSION(S): These results suggest that stressful life events may be associated with decreased semen quality in fertile men. The experience of psychosocial stress may be a modifiable factor in the development of idiopathic infertility. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
OBJECTIVE: To examine the association between stressful life events and semen parameters. DESIGN: Cross-sectional analysis in a pregnancy cohort study. SETTING: Prenatal clinics in five U.S. cities. PATIENT(S): Fertile men (n = 744) in the Study for Future Families, a cohort study of pregnant women and their partners. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Sperm concentration, percent motile, and percent normal morphology and classification above/below World Health Organization (WHO) cutoffs for semen quality. RESULT(S): After adjusting for confounders, men reporting 2+ recent stressful life events had an increased risk of being classified below WHO thresholds for "normal" defined by concentration, motility, and morphology criteria compared with men reporting <2 stressful life events (odds ratio [OR] = 2.06; 95% confidence interval [CI], 1.18, 3.61; OR = 1.54; 95% CI, 1.04, 2.29; OR = 1.93; 95% CI, 1.02, 3.66 for concentration, motility and morphology, respectively). Men experiencing 2+ stressful life events had lower sperm concentration (log scale, beta = -0.25; 95% CI, -0.38, -0.11) and lower percent motile sperm (beta = -1.95; 95% CI, -3.98, 0.07), but percent normal morphology was less affected. CONCLUSION(S): These results suggest that stressful life events may be associated with decreased semen quality in fertile men. The experience of psychosocial stress may be a modifiable factor in the development of idiopathic infertility. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Authors: Ti-Fei Yuan; Ang Li; Xin Sun; Huan Ouyang; Carlos Campos; Nuno B F Rocha; Oscar Arias-Carrión; Sergio Machado; Gonglin Hou; Kwok Fai So Journal: Mol Neurobiol Date: 2015-11-16 Impact factor: 5.590
Authors: Teresa Janevic; Linda G Kahn; Paul Landsbergis; Piera M Cirillo; Barbara A Cohn; Xinhua Liu; Pam Factor-Litvak Journal: Fertil Steril Date: 2014-05-23 Impact factor: 7.329
Authors: Ryan C Lewis; Lidia Mínguez-Alarcón; John D Meeker; Paige L Williams; Gabor Mezei; Jennifer B Ford; Russ Hauser Journal: Reprod Toxicol Date: 2016-11-09 Impact factor: 3.143
Authors: A Ferlin; A E Calogero; C Krausz; F Lombardo; D Paoli; R Rago; C Scarica; M Simoni; C Foresta; V Rochira; E Sbardella; S Francavilla; G Corona Journal: J Endocrinol Invest Date: 2022-01-24 Impact factor: 4.256
Authors: Emily S Barrett; Lauren E Parlett; Sheela Sathyanarayana; J Bruce Redmon; Ruby H N Nguyen; Shanna H Swan Journal: Paediatr Perinat Epidemiol Date: 2015-11-17 Impact factor: 3.980
Authors: S W Thurston; J Mendiola; A R Bellamy; H Levine; C Wang; A Sparks; J B Redmon; E Z Drobnis; S H Swan Journal: Andrology Date: 2015-11-24 Impact factor: 3.842
Authors: Craig James McKinnon; Elizabeth Elliott Hatch; Olivia R Orta; Kenneth J Rothman; Michael L Eisenberg; Johanna Wefes-Potter; Lauren A Wise Journal: J Occup Health Psychol Date: 2021-07-29