Literature DB >> 19228626

Metabolic enzymes as oncogenes or tumor suppressors.

Craig B Thompson.   

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Year:  2009        PMID： 19228626      PMCID： PMC2848669          DOI： 10.1056/NEJMe0810213

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   176.079


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  12 in total

1.  Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle.

Authors:  Dyonne T Hartong; Mayura Dange; Terri L McGee; Eliot L Berson; Thaddeus P Dryja; Roberta F Colman
Journal:  Nat Genet       Date:  2008-09-21       Impact factor: 38.330

Review 2.  Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

Authors:  A King; M A Selak; E Gottlieb
Journal:  Oncogene       Date:  2006-08-07       Impact factor: 9.867

3.  Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.

Authors:  Elaine D MacKenzie; Mary A Selak; Daniel A Tennant; Lloyd J Payne; Stuart Crosby; Casper M Frederiksen; David G Watson; Eyal Gottlieb
Journal:  Mol Cell Biol       Date:  2007-02-26       Impact factor: 4.272

4.  NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases.

Authors:  Jong Kyun Lee; Mouad Edderkaoui; Patrick Truong; Izumi Ohno; Kee-Taek Jang; Andrea Berti; Stephen J Pandol; Anna S Gukovskaya
Journal:  Gastroenterology       Date:  2007-08-14       Impact factor: 22.682

5.  Analysis of the IDH1 codon 132 mutation in brain tumors.

Authors:  Jörg Balss; Jochen Meyer; Wolf Mueller; Andrey Korshunov; Christian Hartmann; Andreas von Deimling
Journal:  Acta Neuropathol       Date:  2008-11-05       Impact factor: 17.088

6.  Small interfering RNA-mediated silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase enhances the sensitivity of HeLa cells toward tumor necrosis factor-alpha and anticancer drugs.

Authors:  In Sup Kil; Sung Youl Kim; Sun Joo Lee; Jeen-Woo Park
Journal:  Free Radic Biol Med       Date:  2007-07-20       Impact factor: 7.376

7.  Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity.

Authors:  Xiang Xu; Jingyue Zhao; Zhen Xu; Baozhen Peng; Qiuhua Huang; Eddy Arnold; Jianping Ding
Journal:  J Biol Chem       Date:  2004-06-01       Impact factor: 5.157

Review 8.  The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.

Authors:  Ralph J DeBerardinis; Julian J Lum; Georgia Hatzivassiliou; Craig B Thompson
Journal:  Cell Metab       Date:  2008-01       Impact factor: 27.287

9.  An integrated genomic analysis of human glioblastoma multiforme.

Authors:  D Williams Parsons; Siân Jones; Xiaosong Zhang; Jimmy Cheng-Ho Lin; Rebecca J Leary; Philipp Angenendt; Parminder Mankoo; Hannah Carter; I-Mei Siu; Gary L Gallia; Alessandro Olivi; Roger McLendon; B Ahmed Rasheed; Stephen Keir; Tatiana Nikolskaya; Yuri Nikolsky; Dana A Busam; Hanna Tekleab; Luis A Diaz; James Hartigan; Doug R Smith; Robert L Strausberg; Suely Kazue Nagahashi Marie; Sueli Mieko Oba Shinjo; Hai Yan; Gregory J Riggins; Darell D Bigner; Rachel Karchin; Nick Papadopoulos; Giovanni Parmigiani; Bert Vogelstein; Victor E Velculescu; Kenneth W Kinzler
Journal:  Science       Date:  2008-09-04       Impact factor: 47.728

10.  IDH1 and IDH2 mutations in gliomas.

Authors:  Hai Yan; D Williams Parsons; Genglin Jin; Roger McLendon; B Ahmed Rasheed; Weishi Yuan; Ivan Kos; Ines Batinic-Haberle; Siân Jones; Gregory J Riggins; Henry Friedman; Allan Friedman; David Reardon; James Herndon; Kenneth W Kinzler; Victor E Velculescu; Bert Vogelstein; Darell D Bigner
Journal:  N Engl J Med       Date:  2009-02-19       Impact factor: 176.079
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  89 in total

1.  Unraveling the complex regulatory relationships between metabolism and signal transduction in cancer.

Authors:  Michelle L Wynn; Sofia D Merajver; Santiago Schnell
Journal:  Adv Exp Med Biol       Date:  2012       Impact factor: 2.622

Review 2.  Cellular metabolism and disease: what do metabolic outliers teach us?

Authors:  Ralph J DeBerardinis; Craig B Thompson
Journal:  Cell       Date:  2012-03-16       Impact factor: 41.582

Review 3.  The role of mitochondria in pulmonary vascular remodeling.

Authors:  Peter Dromparis; Gopinath Sutendra; Evangelos D Michelakis
Journal:  J Mol Med (Berl)       Date:  2010-08-24       Impact factor: 4.599

4.  Neuro-oncology: Isocitrate dehydrogenase mutations in low-grade gliomas.

Authors:  David Schiff; Benjamin W Purow
Journal:  Nat Rev Neurol       Date:  2009-06       Impact factor: 42.937

5.  Prevalence and Prognostic Value of IDH1 R132 Mutation in Newly Diagnosed AML Egyptian Patients with Normal Karyotype.

Authors:  Dalia Salem; Sherin Abd El-Aziz; Nadia El-Menshawy; Tarek Abouzeid; Mohamed Ebrahim
Journal:  Indian J Hematol Blood Transfus       Date:  2016-02-18       Impact factor: 0.900

6.  IDH1 gene mutations: a new paradigm in glioma prognosis and therapy?

Authors:  Marianne Labussiere; Marc Sanson; Ahmed Idbaih; Jean-Yves Delattre
Journal:  Oncologist       Date:  2010-02-04

7.  Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.

Authors:  Jason W Locasale; Alexandra R Grassian; Tamar Melman; Costas A Lyssiotis; Katherine R Mattaini; Adam J Bass; Gregory Heffron; Christian M Metallo; Taru Muranen; Hadar Sharfi; Atsuo T Sasaki; Dimitrios Anastasiou; Edouard Mullarky; Natalie I Vokes; Mika Sasaki; Rameen Beroukhim; Gregory Stephanopoulos; Azra H Ligon; Matthew Meyerson; Andrea L Richardson; Lynda Chin; Gerhard Wagner; John M Asara; Joan S Brugge; Lewis C Cantley; Matthew G Vander Heiden
Journal:  Nat Genet       Date:  2011-07-31       Impact factor: 38.330

8.  Curative role of pantothenic acid in brain damage of gamma irradiated rats.

Authors:  Shedid Sm; Saada Hn; Eltahawy Na; Hammad As
Journal:  Indian J Clin Biochem       Date:  2017-08-07

9.  How molecular testing can help (and hurt) in the workup of gliomas.

Authors:  Kenneth Clark; Zoya Voronovich; Craig Horbinski
Journal:  Am J Clin Pathol       Date:  2013-03       Impact factor: 2.493

10.  The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma.

Authors:  Fonnet E Bleeker; Nadia A Atai; Simona Lamba; Ard Jonker; Denise Rijkeboer; Klazien S Bosch; Wikky Tigchelaar; Dirk Troost; W Peter Vandertop; Alberto Bardelli; Cornelis J F Van Noorden
Journal:  Acta Neuropathol       Date:  2010-02-04       Impact factor: 17.088
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