Literature DB >> 19217371

Reprogramming therapeutics: iPS cell prospects for neurodegenerative disease.

Asa Abeliovich1, Claudia A Doege.   

Abstract

The recent description of somatic cell reprogramming to an embryonic stem (ES) cell-like phenotype, termed induced pluripotent stem (iPS) cell technology, presents an exciting potential venue toward cell-based therapeutics and disease models for neurodegenerative disorders. Two recent studies (Dimos et al. and Ebert et al.) describe the initial characterization of neurodegenerative disease patient-derived iPS cell cultures as proof of concept for the utility of this technology.

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Year:  2009        PMID： 19217371      PMCID： PMC3659427          DOI： 10.1016/j.neuron.2009.01.024

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  15 in total

1.  Transplantation of embryonic dopamine neurons for severe Parkinson's disease.

Authors:  C R Freed; P E Greene; R E Breeze; W Y Tsai; W DuMouchel; R Kao; S Dillon; H Winfield; S Culver; J Q Trojanowski; D Eidelberg; S Fahn
Journal:  N Engl J Med       Date:  2001-03-08       Impact factor: 91.245

Review 2.  Parkinsonism genes: culprits and clues.

Authors:  Asa Abeliovich; M Flint Beal
Journal:  J Neurochem       Date:  2006-07-06       Impact factor: 5.372

3.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

4.  Induced pluripotent stem cell lines derived from human somatic cells.

Authors:  Junying Yu; Maxim A Vodyanik; Kim Smuga-Otto; Jessica Antosiewicz-Bourget; Jennifer L Frane; Shulan Tian; Jeff Nie; Gudrun A Jonsdottir; Victor Ruotti; Ron Stewart; Igor I Slukvin; James A Thomson
Journal:  Science       Date:  2007-11-20       Impact factor: 47.728

5.  Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors:  Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal:  Cell       Date:  2007-11-30       Impact factor: 41.582

6.  Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.

Authors:  Jacob Hanna; Marius Wernig; Styliani Markoulaki; Chiao-Wang Sun; Alexander Meissner; John P Cassady; Caroline Beard; Tobias Brambrink; Li-Chen Wu; Tim M Townes; Rudolf Jaenisch
Journal:  Science       Date:  2007-12-06       Impact factor: 47.728

7.  Generation of germline-competent induced pluripotent stem cells.

Authors:  Keisuke Okita; Tomoko Ichisaka; Shinya Yamanaka
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

8.  In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state.

Authors:  Marius Wernig; Alexander Meissner; Ruth Foreman; Tobias Brambrink; Manching Ku; Konrad Hochedlinger; Bradley E Bernstein; Rudolf Jaenisch
Journal:  Nature       Date:  2007-06-06       Impact factor: 49.962

9.  Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease.

Authors:  Marius Wernig; Jian-Ping Zhao; Jan Pruszak; Eva Hedlund; Dongdong Fu; Frank Soldner; Vania Broccoli; Martha Constantine-Paton; Ole Isacson; Rudolf Jaenisch
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-07       Impact factor: 11.205

10.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors:  Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal:  Nat Biotechnol       Date:  2007-11-30       Impact factor: 54.908
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  14 in total

1.  Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons.

Authors:  Liang Qiang; Ryousuke Fujita; Toru Yamashita; Sergio Angulo; Herve Rhinn; David Rhee; Claudia Doege; Lily Chau; Laetitia Aubry; William B Vanti; Herman Moreno; Asa Abeliovich
Journal:  Cell       Date:  2011-08-05       Impact factor: 41.582

2.  Derivation, culture, and characterization of VUB hESC lines.

Authors:  Ileana Mateizel; Claudia Spits; Martine De Rycke; Inge Liebaers; Karen Sermon
Journal:  In Vitro Cell Dev Biol Anim       Date:  2010-03-12       Impact factor: 2.416

3.  Genotyping, generation and proteomic profiling of the first human autosomal dominant osteopetrosis type II-specific induced pluripotent stem cells.

Authors:  Minglin Ou; Chunhong Li; Donge Tang; Wen Xue; Yong Xu; Peng Zhu; Bo Li; Jiansheng Xie; Jiejing Chen; Weiguo Sui; Lianghong Yin; Yong Dai
Journal:  Stem Cell Res Ther       Date:  2019-08-14       Impact factor: 6.832

4.  Adapting human pluripotent stem cells to high-throughput and high-content screening.

Authors:  Sabrina C Desbordes; Lorenz Studer
Journal:  Nat Protoc       Date:  2012-12-20       Impact factor: 13.491

Review 5.  Induced Pluripotent Stem Cells for Disease Modeling and Drug Discovery in Neurodegenerative Diseases.

Authors:  Lei Cao; Lan Tan; Teng Jiang; Xi-Chen Zhu; Jin-Tai Yu
Journal:  Mol Neurobiol       Date:  2014-08-23       Impact factor: 5.590

6.  Four decades of neurodegenerative disease research: how far we have come!

Authors:  Anne B Young
Journal:  J Neurosci       Date:  2009-10-14       Impact factor: 6.167

7.  β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.

Authors:  Shinsuke Niwa; Hironori Takahashi; Nobutaka Hirokawa
Journal:  EMBO J       Date:  2013-03-15       Impact factor: 11.598

8.  Comparing The Effects of Small Molecules BIX-01294, Bay K8644, RG-108 and Valproic Acid, and Their Different Combinations on Induction of Pluripotency Marker-Genes by Oct4 in The Mouse Brain.

Authors:  Sareh Asadi; Samaneh Dehghan; Maryam Hajikaram; Seyed Javad Mowla; Abolhassan Ahmadiani Ahmadiani; Mohammad Javan
Journal:  Cell J       Date:  2015-01-13       Impact factor: 2.479

Review 9.  Nutraceuticals against Neurodegeneration: A Mechanistic Insight.

Authors:  Vivekkumar P Dadhania; Priyanka P Trivedi; Ajit Vikram; Durga Nand Tripathi
Journal:  Curr Neuropharmacol       Date:  2016       Impact factor: 7.363

Review 10.  Induced pluripotent stem cells to model and treat neurogenetic disorders.

Authors:  Hansen Wang; Laurie C Doering
Journal:  Neural Plast       Date:  2012-07-19       Impact factor: 3.599
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