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Literature DB >> 19194660

ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr.

John Overington.

Abstract

Mesh：

Substances：
Proteins

Year: 2009 PMID： 19194660 DOI： 10.1007/s10822-009-9260-9

Source DB: PubMed Journal: J Comput Aided Mol Des ISSN： 0920-654X Impact factor: 3.686

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4 in total

Review 1. Recent developments of the chemistry development kit (CDK) - an open-source java library for chemo- and bioinformatics.

Authors: Christoph Steinbeck; Christian Hoppe; Stefan Kuhn; Matteo Floris; Rajarshi Guha; Egon L Willighagen
Journal: Curr Pharm Des Date: 2006 Impact factor: 3.116

Review 2. How many drug targets are there?

Authors: John P Overington; Bissan Al-Lazikani; Andrew L Hopkins
Journal: Nat Rev Drug Discov Date: 2006-12 Impact factor: 84.694

Review 3. Genomic-scale prioritization of drug targets: the TDR Targets database.

Authors: Fernán Agüero; Bissan Al-Lazikani; Martin Aslett; Matthew Berriman; Frederick S Buckner; Robert K Campbell; Santiago Carmona; Ian M Carruthers; A W Edith Chan; Feng Chen; Gregory J Crowther; Maria A Doyle; Christiane Hertz-Fowler; Andrew L Hopkins; Gregg McAllister; Solomon Nwaka; John P Overington; Arnab Pain; Gaia V Paolini; Ursula Pieper; Stuart A Ralph; Aaron Riechers; David S Roos; Andrej Sali; Dhanasekaran Shanmugam; Takashi Suzuki; Wesley C Van Voorhis; Christophe L M J Verlinde
Journal: Nat Rev Drug Discov Date: 2008-10-17 Impact factor: 84.694

4. The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics.

Authors: Christoph Steinbeck; Yongquan Han; Stefan Kuhn; Oliver Horlacher; Edgar Luttmann; Egon Willighagen
Journal: J Chem Inf Comput Sci Date: 2003 Mar-Apr

4 in total

57 in total

10. Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex.

Authors: Aditya J Desai; Polo C H Lam; Andrew Orry; Ruben Abagyan; Arthur Christopoulos; Patrick M Sexton; Laurence J Miller
Journal: J Med Chem Date: 2015-12-10 Impact factor: 7.446

ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr.

Review 1. Recent developments of the chemistry development kit (CDK) - an open-source java library for chemo- and bioinformatics.

Review 2. How many drug targets are there?

Review 3. Genomic-scale prioritization of drug targets: the TDR Targets database.

4. The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics.

1. Can we really do computer-aided drug design?

2. IUPHAR-DB: an open-access, expert-curated resource for receptor and ion channel research.

Review 3. PubChem as a public resource for drug discovery.

4. The Recognition of Identical Ligands by Unrelated Proteins.

5. Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor.

6. Reactome pathway analysis to enrich biological discovery in proteomics data sets.

Review 7. Exploring chemical space for drug discovery using the chemical universe database.

8. Fragment-based in silico modeling of multi-target inhibitors against breast cancer-related proteins.

9. The ChEMBL database as linked open data.

10. Molecular Mechanism of Action of Triazolobenzodiazepinone Agonists of the Type 1 Cholecystokinin Receptor. Possible Cooperativity across the Receptor Homodimeric Complex.