Literature DB >> 22778867

IUPHAR-DB: an open-access, expert-curated resource for receptor and ion channel research.

Joanna L Sharman1, Chidochangu P Mpamhanga.   

Abstract

This contribution highlights efforts by the International Union of Basic and Clinical Pharmacology (IUPHAR) Nomenclature Committee (NC-IUPHAR) to classify human receptors and ion channels, to document their properties, and to recommend ligands that are useful for characterization. This effort has inspired the creation of an online database (IUPHAR-DB), which is intended to provide free information to all scientists, summarized from primary literature by experts.

Entities:  

Keywords:  Drug target; GPCR; biocuration; chemical tool; database; ion channel

Mesh:

Substances:

Year:  2011        PMID: 22778867      PMCID: PMC3369752          DOI: 10.1021/cn200025w

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN: 1948-7193            Impact factor:   4.418


  16 in total

1.  The Protein Data Bank.

Authors:  H M Berman; J Westbrook; Z Feng; G Gilliland; T N Bhat; H Weissig; I N Shindyalov; P E Bourne
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

Review 2.  Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.

Authors:  C A Lipinski; F Lombardo; B W Dominy; P J Feeney
Journal:  Adv Drug Deliv Rev       Date:  2001-03-01       Impact factor: 15.470

Review 3.  The druggable genome.

Authors:  Andrew L Hopkins; Colin R Groom
Journal:  Nat Rev Drug Discov       Date:  2002-09       Impact factor: 84.694

Review 4.  Resolution of controversies in drug/receptor interactions by protein structure. Limitations and pharmacological solutions.

Authors:  Michael Spedding
Journal:  Neuropharmacology       Date:  2010-08-13       Impact factor: 5.250

5.  Pharma pursues novel models for academic collaboration.

Authors:  Bethan Hughes
Journal:  Nat Rev Drug Discov       Date:  2008-08       Impact factor: 84.694

Review 6.  International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.

Authors:  Jean-Philippe Pin; Richard Neubig; Michel Bouvier; Lakshmi Devi; Marta Filizola; Jonathan A Javitch; Martin J Lohse; Graeme Milligan; Krzysztof Palczewski; Marc Parmentier; Michael Spedding
Journal:  Pharmacol Rev       Date:  2007-03       Impact factor: 25.468

7.  Ensembl 2011.

Authors:  Paul Flicek; M Ridwan Amode; Daniel Barrell; Kathryn Beal; Simon Brent; Yuan Chen; Peter Clapham; Guy Coates; Susan Fairley; Stephen Fitzgerald; Leo Gordon; Maurice Hendrix; Thibaut Hourlier; Nathan Johnson; Andreas Kähäri; Damian Keefe; Stephen Keenan; Rhoda Kinsella; Felix Kokocinski; Eugene Kulesha; Pontus Larsson; Ian Longden; William McLaren; Bert Overduin; Bethan Pritchard; Harpreet Singh Riat; Daniel Rios; Graham R S Ritchie; Magali Ruffier; Michael Schuster; Daniel Sobral; Giulietta Spudich; Y Amy Tang; Stephen Trevanion; Jana Vandrovcova; Albert J Vilella; Simon White; Steven P Wilder; Amonida Zadissa; Jorge Zamora; Bronwen L Aken; Ewan Birney; Fiona Cunningham; Ian Dunham; Richard Durbin; Xosé M Fernández-Suarez; Javier Herrero; Tim J P Hubbard; Anne Parker; Glenn Proctor; Jan Vogel; Stephen M J Searle
Journal:  Nucleic Acids Res       Date:  2010-11-02       Impact factor: 16.971

8.  IUPHAR-DB: new receptors and tools for easy searching and visualization of pharmacological data.

Authors:  Joanna L Sharman; Chidochangu P Mpamhanga; Michael Spedding; Pierre Germain; Bart Staels; Catherine Dacquet; Vincent Laudet; Anthony J Harmar
Journal:  Nucleic Acids Res       Date:  2010-11-17       Impact factor: 16.971

9.  Database resources of the National Center for Biotechnology Information.

Authors:  Eric W Sayers; Tanya Barrett; Dennis A Benson; Evan Bolton; Stephen H Bryant; Kathi Canese; Vyacheslav Chetvernin; Deanna M Church; Michael Dicuccio; Scott Federhen; Michael Feolo; Lewis Y Geer; Wolfgang Helmberg; Yuri Kapustin; David Landsman; David J Lipman; Zhiyong Lu; Thomas L Madden; Tom Madej; Donna R Maglott; Aron Marchler-Bauer; Vadim Miller; Ilene Mizrachi; James Ostell; Anna Panchenko; Kim D Pruitt; Gregory D Schuler; Edwin Sequeira; Stephen T Sherry; Martin Shumway; Karl Sirotkin; Douglas Slotta; Alexandre Souvorov; Grigory Starchenko; Tatiana A Tatusova; Lukas Wagner; Yanli Wang; W John Wilbur; Eugene Yaschenko; Jian Ye
Journal:  Nucleic Acids Res       Date:  2009-11-12       Impact factor: 16.971

10.  DrugBank: a knowledgebase for drugs, drug actions and drug targets.

Authors:  David S Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali
Journal:  Nucleic Acids Res       Date:  2007-11-29       Impact factor: 16.971

View more
  2 in total

1.  A uniquely adaptable pore is consistent with NALCN being an ion sensor.

Authors:  Adriano Senatore; J David Spafford
Journal:  Channels (Austin)       Date:  2013-02-26       Impact factor: 2.581

2.  Using machine learning tools for protein database biocuration assistance.

Authors:  Caroline König; Ilmira Shaim; Alfredo Vellido; Enrique Romero; René Alquézar; Jesús Giraldo
Journal:  Sci Rep       Date:  2018-07-05       Impact factor: 4.379

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.