Literature DB >> 19180668

Directed evolution of enzymes: Library screening strategies.

Hans Leemhuis1, Ronan M Kelly, Lubbert Dijkhuizen.   

Abstract

Directed evolution has become the preferred engineering approach to generate tailor-made enzymes. The method follows the design guidelines of nature: Darwinian selection of genetic variants. This review discusses the different stages of directed evolution experiments with the focus on developments in screening and selection procedures. (c) 2009 IUBMB IUBMB Life 61(3): 222-228, 2009.

Year:  2009        PMID： 19180668     DOI： 10.1002/iub.165

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  22 in total

1.  Facile Enzymatic Synthesis of Ketoses.

Authors:  Liuqing Wen; Kenneth Huang; Mohui Wei; Jeffrey Meisner; Yunpeng Liu; Kristina Garner; Lanlan Zang; Xuan Wang; Xu Li; Junqiang Fang; Houcheng Zhang; Peng George Wang
Journal:  Angew Chem Int Ed Engl       Date:  2015-08-14       Impact factor: 15.336

Review 2.  Directed evolution drives the next generation of biocatalysts.

Authors:  Nicholas J Turner
Journal:  Nat Chem Biol       Date:  2009-08       Impact factor: 15.040

3.  mRNA display for the selection and evolution of enzymes from in vitro-translated protein libraries.

Authors:  Burckhard Seelig
Journal:  Nat Protoc       Date:  2011-03-31       Impact factor: 13.491

4.  Sequence-structural features and evolutionary relationships of family GH57 α-amylases and their putative α-amylase-like homologues.

Authors:  Stefan Janeček; Karol Blesák
Journal:  Protein J       Date:  2011-08       Impact factor: 2.371

5.  Liposome display for in vitro selection and evolution of membrane proteins.

Authors:  Satoshi Fujii; Tomoaki Matsuura; Takeshi Sunami; Takehiro Nishikawa; Yasuaki Kazuta; Tetsuya Yomo
Journal:  Nat Protoc       Date:  2014-06-05       Impact factor: 13.491

Review 6.  Microbial conversion of pyrolytic products to biofuels: a novel and sustainable approach toward second-generation biofuels.

Authors:  Zia Ul Islam; Yu Zhisheng; El Barbary Hassan; Chang Dongdong; Zhang Hongxun
Journal:  J Ind Microbiol Biotechnol       Date:  2015-10-03       Impact factor: 3.346

Review 7.  Rapid prototyping of microbial cell factories via genome-scale engineering.

Authors:  Tong Si; Han Xiao; Huimin Zhao
Journal:  Biotechnol Adv       Date:  2014-11-20       Impact factor: 14.227

8.  Replication methods and tools in high-throughput cultivation processes - recognizing potential variations of growth and product formation by on-line monitoring.

Authors:  Robert Huber; Thomas G Palmen; Nadine Ryk; Anne-Kathrin Hillmer; Karina Luft; Frank Kensy; Jochen Büchs
Journal:  BMC Biotechnol       Date:  2010-03-16       Impact factor: 2.563

Review 9.  Engineering acyl-homoserine lactone-interfering enzymes toward bacterial control.

Authors:  Raphaël Billot; Laure Plener; Pauline Jacquet; Mikael Elias; Eric Chabrière; David Daudé
Journal:  J Biol Chem       Date:  2020-07-20       Impact factor: 5.157

Review 10.  Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications.

Authors:  Hans Leemhuis; Ronan M Kelly; Lubbert Dijkhuizen
Journal:  Appl Microbiol Biotechnol       Date:  2009-09-18       Impact factor: 4.813
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