Literature DB >> 19175949

Consanguinity in Lebanon: prevalence, distribution and determinants.

Bernadette Barbour1, Pascale Salameh.   

Abstract

The union of individuals with a common ancestor may lead to serious health consequences in their offspring. Consanguinity is high in Middle Eastern communities; it was around 26% in 1988. The objective of this study was to determine the prevalence of consanguinity in Beirut and other Lebanese regions, and its associated factors in different subgroups. The cross-sectional study was performed on a convenience sample of married women in Lebanon. The women were administered a standardized questionnaire in a face-to-face interview by independent enquirers. Among 1556 women, the overall prevalence of consanguineous marriages was 35.5%, and the consanguinity coefficient was 0.020; 968 marriages (62.2%) were not consanguineous, 492 (31.6%) were first cousin, 61 (3.9%) were second cousin and 36 (2.3%) had lower degrees of consanguinity. Beirut suburb dwelling, low education subgroups, women working in the home and non-Christian religion presented the highest rates of consanguinity (p<0.05). Consanguinity is associated with couples' nulliparity and child chronic morbidity. Factors that could affect consanguinity are having consanguineous parents, having a favourable opinion towards consanguinity, choosing a spouse for religious reasons, particularly in Islam, woman having a low education, woman working in the home and women thinking that consanguinity would not lead to serious diseases. Consanguinity is therefore still a prevailing problem in Lebanon. Specific health education, and genetic counselling in particular, are suggested to explain the consequences of consanguinity to the general population and to help couples make informed choices.

Entities:  

Mesh:

Year:  2009        PMID: 19175949     DOI: 10.1017/S0021932009003290

Source DB:  PubMed          Journal:  J Biosoc Sci        ISSN: 0021-9320


  26 in total

1.  A review of the diverse genetic disorders in the Lebanese population: highlighting the urgency for community genetic services.

Authors:  Ghunwa Nakouzi; Khalil Kreidieh; Soha Yazbek
Journal:  J Community Genet       Date:  2014-09-27

2.  A 5-year survey of biopsy proven kidney diseases in Lebanon: significant variation in prevalence of primary glomerular diseases by age, population structure and consanguinity.

Authors:  Hussein H Karnib; Ali G Gharavi; Georges Aftimos; Ziyad Mahfoud; Reem Saad; Elias Gemayel; Badiaa Masri; Shafika Assaad; Kamal F Badr; Fuad N Ziyadeh
Journal:  Nephrol Dial Transplant       Date:  2010-06-04       Impact factor: 5.992

3.  Autosomal short tandem repeat variations and population genetic data on 23 systems in seven major subpopulations from Lebanon.

Authors:  Ansar El Andari; Mira Khazzouh; Issam Mansour
Journal:  Int J Legal Med       Date:  2018-04-07       Impact factor: 2.686

4.  Genome-wide inbreeding estimation within Lebanese communities using SNP arrays.

Authors:  Nadine Jalkh; Mourad Sahbatou; Eliane Chouery; André Megarbane; Anne-Louise Leutenegger; Jean-Louis Serre
Journal:  Eur J Hum Genet       Date:  2014-11-26       Impact factor: 4.246

5.  Awareness Campaign for the Early Detection of Growth Disorders in Public School Children in North Lebanon.

Authors:  Femia Hayek; Bouchra Berro; Wissam Fayad
Journal:  Ethn Dis       Date:  2016-07-21       Impact factor: 1.847

Review 6.  Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases.

Authors:  Yanna Ko; Rhys Butcher; Rupert W Leong
Journal:  World J Gastroenterol       Date:  2014-02-07       Impact factor: 5.742

7.  Association of Autism with Maternal Infections, Perinatal and Other Risk Factors: A Case-Control Study.

Authors:  Dikran Richard Guisso; Fadi S Saadeh; Dahlia Saab; Joud El Deek; Sarah Chamseddine; Hadi Abou-El-Hassan; Ghidaa Majari; Rose-Mary Boustany
Journal:  J Autism Dev Disord       Date:  2018-06

8.  Allele frequency of variants reported to cause adenine phosphoribosyltransferase deficiency.

Authors:  Hrafnhildur L Runolfsdottir; John A Sayer; Olafur S Indridason; Vidar O Edvardsson; Brynjar O Jensson; Gudny A Arnadottir; Sigurjon A Gudjonsson; Run Fridriksdottir; Hildigunnur Katrinardottir; Daniel Gudbjartsson; Unnur Thorsteinsdottir; Patrick Sulem; Kari Stefansson; Runolfur Palsson
Journal:  Eur J Hum Genet       Date:  2021-03-11       Impact factor: 5.351

9.  Consanguinity and reproductive health among Arabs.

Authors:  Ghazi O Tadmouri; Pratibha Nair; Tasneem Obeid; Mahmoud T Al Ali; Najib Al Khaja; Hanan A Hamamy
Journal:  Reprod Health       Date:  2009-10-08       Impact factor: 3.223

10.  Untreated chronic lymphocytic leukemia in Lebanese patients: an observational study using standard karyotyping and FISH.

Authors:  Elie El Rassy; Alain Chebly; Rima Korban; Warde Semaan; Ziad Bakouny; Tarek Assi; Hampig Raphael Kourie; Fadi El Karak; Eliane Chouery; Joseph Kattan
Journal:  Int J Hematol Oncol       Date:  2017-12-21
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.