Literature DB >> 19171686

Impact of blood cultures drawn by phlebotomy on contamination rates and health care costs in a hospital emergency department.

Rita M Gander1, Linda Byrd, Michael DeCrescenzo, Shaina Hirany, Michelle Bowen, Judy Baughman.   

Abstract

We conducted a prospective comparison of blood culture contamination rates associated with dedicated phlebotomists and nonphlebotomy staff in the emergency department (ED) at Parkland Memorial Hospital in Dallas, TX. In addition, hospital charges and lengths of stay were determined for patients with negative, false-positive, and true-positive blood culture results. A total of 5,432 blood culture collections from two ED areas, the western wing of the ED (ED west) and the nonwestern wing of the ED (ED nonwest), were evaluated over a 13-month period. Phlebotomists drew 2,012 (55%) of the blood cultures in ED west while nonphlebotomy staff drew 1,650 (45%) in ED west and 1,770 (100%) in ED nonwest. The contamination rates of blood cultures collected by phlebotomists were significantly lower than those collected by nonphlebotomists in ED west (62/2,012 [3.1%] versus 122/1,650 [7.4%]; P < 0.001). Similar results were observed when rates between phlebotomists in ED west and nonphlebotomy staff in ED nonwest were compared (62/2,012 [3.1%] versus 100/1,770 [5.6%]; P < 0.001). Comparison of median patient charges between negative and false-positive episodes ($18,752 versus $27,472) showed $8,720 in additional charges per contamination event while the median length of stay increased marginally from 4 to 5 days. By utilizing phlebotomists to collect blood cultures in the ED, contamination rates were lowered to recommended levels, with projected reductions in patient charges of approximately $4.1 million per year.

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Year:  2009        PMID: 19171686      PMCID: PMC2668314          DOI: 10.1128/JCM.02162-08

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  18 in total

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Authors:  T Schulin; A Voss
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2.  Optimal testing parameters for blood cultures.

Authors:  F R Cockerill; J W Wilson; E A Vetter; K M Goodman; C A Torgerson; W S Harmsen; C D Schleck; D M Ilstrup; J A Washington; W R Wilson
Journal:  Clin Infect Dis       Date:  2004-05-25       Impact factor: 9.079

3.  Reduction of blood culture contamination rate by an educational intervention.

Authors:  S Eskira; J Gilad; P Schlaeffer; E Hyam; N Peled; I Karakis; K Riesenberg; F Schlaeffer; A Borer
Journal:  Clin Microbiol Infect       Date:  2006-08       Impact factor: 8.067

4.  Contaminant blood cultures and resource utilization. The true consequences of false-positive results.

Authors:  D W Bates; L Goldman; T H Lee
Journal:  JAMA       Date:  1991-01-16       Impact factor: 56.272

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Authors:  R R MacGregor; H N Beaty
Journal:  Arch Intern Med       Date:  1972-07

6.  Blood culture contamination in Tanzania, Malawi, and the United States: a microbiological tale of three cities.

Authors:  Lennox K Archibald; Kisali Pallangyo; Peter Kazembe; L Barth Reller
Journal:  J Clin Microbiol       Date:  2006-10-04       Impact factor: 5.948

7.  The effect of skin disinfection materials on reducing blood culture contamination.

Authors:  R B Schifman; A Pindur
Journal:  Am J Clin Pathol       Date:  1993-05       Impact factor: 2.493

8.  Contamination rates of blood cultures obtained by dedicated phlebotomy vs intravenous catheter.

Authors:  Alonna Norberg; Norman C Christopher; Maria L Ramundo; John R Bower; Shirley A Berman
Journal:  JAMA       Date:  2003-02-12       Impact factor: 56.272

9.  Rapid classification of positive blood cultures. Prospective validation of a multivariate algorithm.

Authors:  D W Bates; T H Lee
Journal:  JAMA       Date:  1992-04-08       Impact factor: 56.272

10.  Staphylococcus epidermidis: an increasing cause of infection in patients with granulocytopenia.

Authors:  J C Wade; S C Schimpff; K A Newman; P H Wiernik
Journal:  Ann Intern Med       Date:  1982-10       Impact factor: 25.391

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  44 in total

1.  Innovation for reducing blood culture contamination: initial specimen diversion technique.

Authors:  Richard G Patton; Timothy Schmitt
Journal:  J Clin Microbiol       Date:  2010-10-13       Impact factor: 5.948

2.  Effect of the initial specimen diversion technique on blood culture contamination rates.

Authors:  Khalifa Binkhamis; Kevin Forward
Journal:  J Clin Microbiol       Date:  2014-01-03       Impact factor: 5.948

3.  Cost analysis of strategies to reduce blood culture contamination in the emergency department: sterile collection kits and phlebotomy teams.

Authors:  Wesley H Self; Thomas R Talbot; Barbara R Paul; Sean P Collins; Michael J Ward
Journal:  Infect Control Hosp Epidemiol       Date:  2014-06-20       Impact factor: 3.254

4.  Dimethyl sulfoxide enhances effectiveness of skin antiseptics and reduces contamination rates of blood cultures.

Authors:  Jeffrey J Tarrand; Paul R LaSala; Xiang-Yang Han; Kenneth V Rolston; Dimitrios P Kontoyiannis
Journal:  J Clin Microbiol       Date:  2012-02-29       Impact factor: 5.948

5.  Blood culture collection through peripheral intravenous catheters increases the risk of specimen contamination among adult emergency department patients.

Authors:  Wesley H Self; Theodore Speroff; Candace D McNaughton; Patty W Wright; Geraldine Miller; James G Johnson; Titus L Daniels; Thomas R Talbot
Journal:  Infect Control Hosp Epidemiol       Date:  2012-03-20       Impact factor: 3.254

6.  Molecular diagnosis of sepsis: New aspects and recent developments.

Authors:  O Liesenfeld; L Lehman; K-P Hunfeld; G Kost
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2014-03-14

7.  The effect of a quality improvement programme reducing blood culture contamination on the detection of bloodstream infection in an emergency department.

Authors:  Paul Robertson; Andrew Russell; Donald J Inverarity
Journal:  J Infect Prev       Date:  2014-12-10

8.  Blood Culture Contaminants in a Paediatric Population Retrospective study from a tertiary hospital in Oman.

Authors:  Mohamed A El-Naggari; Sharef W Al-Mulaabed; Zakaria Al-Muharrmi; Renjith Mani; Rana Abdelrahim; Reem Abdwani
Journal:  Sultan Qaboos Univ Med J       Date:  2017-06-20

9.  Chlorhexidine versus Tincture of Iodine for Reduction of Blood Culture Contamination Rates: a Prospective Randomized Crossover Study.

Authors:  Elizabeth Story-Roller; Melvin P Weinstein
Journal:  J Clin Microbiol       Date:  2016-10-05       Impact factor: 5.948

Review 10.  Practical Guidance for Clinical Microbiology Laboratories: A Comprehensive Update on the Problem of Blood Culture Contamination and a Discussion of Methods for Addressing the Problem

Authors:  Gary V Doern; Karen C Carroll; Daniel J Diekema; Kevin W Garey; Mark E Rupp; Melvin P Weinstein; Daniel J Sexton
Journal:  Clin Microbiol Rev       Date:  2019-10-30       Impact factor: 26.132

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