Literature DB >> 28989406

The effect of a quality improvement programme reducing blood culture contamination on the detection of bloodstream infection in an emergency department.

Paul Robertson1, Andrew Russell2, Donald J Inverarity3.   

Abstract

BACKGROUND: Contaminated blood cultures (BC) generate avoidable costs and prolong hospital stays. To measure our hospital's performance against the recommended standard of <3% BC contamination, we performed a prospective study.
METHODS: We prospectively determined the frequency of contaminated and genuinely positive BC hospital-wide over seven months.
RESULTS: Overall, 73 of 1,829 blood cultures reviewed were contaminated (4.0%). However, distribution of contamination was not uniform. Finding a consistently higher incidence of contamination (11.7%) in our emergency department (ED) than elsewhere in the hospital (2.5%), we adopted a collaborative quality improvement strategy targeted to the ED. A combination of education, modified BC packs and regular feedback of BC results was associated with a significant reduction in contamination (7.4%, p=0.01) over the next six months. Our data suggests that contaminated BC were more likely to have been taken during regular day time hours (odds ratio (OR) 2.7, p=0.012), rather than overnight and were not associated with influxes of new junior medical staff. We found no evidence that the incidence of true bloodstream infection (12.8%) diagnosed by our ED was adversely affected by our intervention (10.7%, p=0.35).
CONCLUSIONS: Using a simple and inexpensive collaborative intervention we reduced BC contamination without adversely affecting the detection of genuine BSI.

Entities:  

Keywords:  Blood culture; bloodstream infection; contamination; educational intervention; quality improvement

Year:  2014        PMID: 28989406      PMCID: PMC5074175          DOI: 10.1177/1757177414561107

Source DB:  PubMed          Journal:  J Infect Prev        ISSN: 1757-1782


  20 in total

1.  Predicting bacteremia at the bedside.

Authors:  Fabián Jaimes; Clara Arango; Giovanni Ruiz; Jorge Cuervo; Juan Botero; Gloria Vélez; Natalia Upegui; Faber Machado
Journal:  Clin Infect Dis       Date:  2004-01-13       Impact factor: 9.079

2.  Effective strategy for decreasing blood culture contamination rates: the experience of a Veterans Affairs Medical Centre.

Authors:  D Youssef; W Shams; B Bailey; T J O'Neil; M A Al-Abbadi
Journal:  J Hosp Infect       Date:  2012-06-27       Impact factor: 3.926

3.  Simple measures to reduce the rate of contamination of blood cultures in Accident and Emergency.

Authors:  M Madeo; T Jackson; C Williams
Journal:  Emerg Med J       Date:  2005-11       Impact factor: 2.740

4.  Contaminant blood cultures and resource utilization. The true consequences of false-positive results.

Authors:  D W Bates; L Goldman; T H Lee
Journal:  JAMA       Date:  1991-01-16       Impact factor: 56.272

5.  Reducing blood culture contamination rates in the emergency department.

Authors:  Andrew D Harding; Susan Bollinger
Journal:  J Emerg Nurs       Date:  2013-01       Impact factor: 1.836

6.  Reducing contamination of peripheral blood cultures in a pediatric emergency department.

Authors:  Tomas A Murillo; Tony K Beavers-May; David English; Vanessa Plummer; Stephanie H Stovall
Journal:  Pediatr Emerg Care       Date:  2011-10       Impact factor: 1.454

7.  Do peripheral blood cultures taken in the emergency department influence clinical management?

Authors:  Philip T Munro; Neil Howie; Jan F Gerstenmaier
Journal:  Emerg Med J       Date:  2007-03       Impact factor: 2.740

8.  Blood culture contamination: a College of American Pathologists Q-Probes study involving 640 institutions and 497134 specimens from adult patients.

Authors:  R B Schifman; C L Strand; F A Meier; P J Howanitz
Journal:  Arch Pathol Lab Med       Date:  1998-03       Impact factor: 5.534

9.  Clinical impact of blood cultures taken in the emergency department.

Authors:  A M Kelly
Journal:  J Accid Emerg Med       Date:  1998-07

10.  Blood cultures ordered in the adult emergency department are rarely useful.

Authors:  David Mountain; Paul M Bailey; Debra O'Brien; George A Jelinek
Journal:  Eur J Emerg Med       Date:  2006-04       Impact factor: 2.799

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  2 in total

1.  Trends in Collection of Microbiological Cultures Across Veterans Affairs Community Living Centers in the United States Over 8 Years.

Authors:  Haley J Appaneal; Aisling R Caffrey; Maria-Stephanie A Hughes; Vrishali V Lopes; Robin L P Jump; Kerry L LaPlante; David M Dosa
Journal:  J Am Med Dir Assoc       Date:  2019-08-26       Impact factor: 4.669

2.  Identification of the main contributors to blood culture contamination at a tertiary care academic medical center.

Authors:  Brianna Sacchetti; Justin Travis; Lisa L Steed; Ginny Webb
Journal:  Infect Prev Pract       Date:  2022-05-24
  2 in total

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