| Literature DB >> 19168976 |
Jidong Wang1, Hui Zhang, Xiaohu Yang, Yue Zhou, Haibin Wang, Hua Bai.
Abstract
Investigation of the bioactive metabolites from the soil-derived actinomycete, Streptomyces sp. HS-HY-071, a new furan-type antibiotic, HS071 (1), was isolated. Its structure was established as methyl 4-hydroxymethyl-2-pentylfuran-3-carboxylate on the basis of extensive 1D and 2D NMR and MS spectral analysis. It exhibited in vitro activity against HCT-116 cell with an IC50 of 18.2 microg/ml.Entities:
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Year: 2008 PMID： 19168976 DOI： 10.1038/ja.2008.82
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649