PURPOSE: To critically review data on the prevalence of depressive symptoms in general intensive care unit (ICU) survivors, risk factors for these symptoms, and their impact on health-related quality of life (HRQOL). METHODS: We conducted a systematic review using Medline, EMBASE, Cochrane Library, CINAHL, PsycINFO, and a hand-search of 13 journals. RESULTS: Fourteen studies were eligible. The median point prevalence of "clinically significant" depressive symptoms was 28% (total n = 1,213). Neither sex nor age were consistent risk factors for post-ICU depression, and severity of illness at ICU admission was consistently not a risk factor. Early post-ICU depressive symptoms were a strong risk factor for subsequent depressive symptoms. Post-ICU depressive symptoms were associated with substantially lower HRQOL. CONCLUSIONS: Depressive symptoms are common in general ICU survivors and negatively impact HRQOL. Future studies should address how factors related to individual patients, critical illness and post-ICU recovery are associated with depression in ICU survivors.
PURPOSE: To critically review data on the prevalence of depressive symptoms in general intensive care unit (ICU) survivors, risk factors for these symptoms, and their impact on health-related quality of life (HRQOL). METHODS: We conducted a systematic review using Medline, EMBASE, Cochrane Library, CINAHL, PsycINFO, and a hand-search of 13 journals. RESULTS: Fourteen studies were eligible. The median point prevalence of "clinically significant" depressive symptoms was 28% (total n = 1,213). Neither sex nor age were consistent risk factors for post-ICU depression, and severity of illness at ICU admission was consistently not a risk factor. Early post-ICU depressive symptoms were a strong risk factor for subsequent depressive symptoms. Post-ICU depressive symptoms were associated with substantially lower HRQOL. CONCLUSIONS:Depressive symptoms are common in general ICU survivors and negatively impact HRQOL. Future studies should address how factors related to individual patients, critical illness and post-ICU recovery are associated with depression in ICU survivors.
Authors: David W Dowdy; Mark P Eid; Artyom Sedrakyan; Pedro A Mendez-Tellez; Peter J Pronovost; Margaret S Herridge; Dale M Needham Journal: Intensive Care Med Date: 2005-04-01 Impact factor: 17.440
Authors: K B Wells; A Stewart; R D Hays; M A Burnam; W Rogers; M Daniels; S Berry; S Greenfield; J Ware Journal: JAMA Date: 1989-08-18 Impact factor: 56.272
Authors: D Steffling; M Ritzka; W Jakob; A Steinbrecher; S Schwab-Malek; B Kaiser; P Hau; S Boy; K Fuchs; U Bogdahn; F Schlachetzki Journal: Nervenarzt Date: 2012-06 Impact factor: 1.214
Authors: Cristina M Pratt; Eliotte L Hirshberg; Jason P Jones; Kathryn G Kuttler; Michael J Lanspa; Emily L Wilson; Ramona O Hopkins; Samuel M Brown Journal: Shock Date: 2015-02 Impact factor: 3.454
Authors: Oscar J Bienvenu; Elizabeth Colantuoni; Pedro A Mendez-Tellez; Victor D Dinglas; Carl Shanholtz; Nadia Husain; Cheryl R Dennison; Margaret S Herridge; Peter J Pronovost; Dale M Needham Journal: Am J Respir Crit Care Med Date: 2011-12-08 Impact factor: 21.405
Authors: James C Jackson; Timothy D Girard; Sharon M Gordon; Jennifer L Thompson; Ayumi K Shintani; Jason W W Thomason; Brenda T Pun; Angelo E Canonico; Janet G Dunn; Gordon R Bernard; Robert S Dittus; E Wesley Ely Journal: Am J Respir Crit Care Med Date: 2010-03-18 Impact factor: 21.405
Authors: JiYeon Choi; Jennifer H Lingler; Michael P Donahoe; Mary Beth Happ; Leslie A Hoffman; Judith A Tate Journal: Heart Lung Date: 2018-05-03 Impact factor: 2.210
Authors: Sharon McKinley; Leanne M Aitken; Jennifer A Alison; Madeleine King; Gavin Leslie; Elizabeth Burmeister; Doug Elliott Journal: Intensive Care Med Date: 2012-02-09 Impact factor: 17.440
Authors: Nicholas A Kolaitis; Allison Soong; Pavan Shrestha; Hanjing Zhuo; John Neuhaus; Patti P Katz; John R Greenland; Jeffrey Golden; Lorriana E Leard; Rupal J Shah; Steven R Hays; Jasleen Kukreja; Mary Ellen Kleinhenz; Paul D Blanc; Jonathan P Singer Journal: J Thorac Cardiovasc Surg Date: 2018-02-22 Impact factor: 5.209