| Literature DB >> 1914458 |
B Jonsson1, B M Landgren, P Eneroth.
Abstract
The influence of three different intrauterine devices on the composition of cervical mucus was studied. The amount of mucin, albumin and immunoglobulin G was estimated. After the insertion of an inert IUD, a decrease in mucin was observed. During copper-IUD use the content of mucin, albumin and IgG was increased in cervical mucus, while weight was not affected. In the levonorgestrel-IUD users, ovulation was inhibited in 2 out of 8 women. Mucus weight was increased. The amounts of mucin, albumin and IgG were not changed. In an in vitro experiment the effect of copper-IUDs on autooxidation of cholesterol was studied. There was an extensive conversion of cholesterol but addition of albumin quenched the oxidation of cholesterol. It is suggested that the increased secretion of albumin induced by copper-IUD users may offer protection against copper-induced cell damage.Entities:
Keywords: Biology; Cervical Mucus; Cervix; Clinical Research; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Agents, Progestin; Contraceptive Methods--pharmacodynamics; Endocrine System; Estradiol; Estrogens; Family Planning; Genitalia; Genitalia, Female; Hormones; Iud, Copper Releasing--pharmacodynamics; Iud, Hormone Releasing--pharmacodynamics; Iud, Unmedicated--pharmacodynamics; Iud--pharmacodynamics; Levonorgestrel; Physiology; Progestational Hormones; Progesterone; Research Methodology; Urogenital System; Uterus
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Year: 1991 PMID： 1914458 DOI： 10.1016/0010-7824(91)90135-3
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375