Literature DB >> 19137303

A simple MRI protocol in patients with clinically suspected appendicitis: results in 138 patients and effect on outcome of appendectomy.

Lodewijk Cobben1, Ingrid Groot, Lucas Kingma, Emile Coerkamp, Julien Puylaert, Johan Blickman.   

Abstract

To establish the value of breathhold magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis. Over a 14-month period, 138 patients clinically suspected of having appendicitis were evaluated prospectively with MRI and comprised the study group. Fast turbo spin-echo breathhold T1, T2 and T2 fat suppression sequences were used in coronal and axial planes. The imaging results were recorded separately and subsequently correlated with clinical, radiological and histopathological follow-up. The effect of imaging strategies in patients suspected of appendicitis on hospital resources was calculated. Sixty-two of the 138 patients had a histopathologically proven appendicitis. MRI determined appendicitis in 63 patients, with one examination being false positive. The resulting sensitivity and specificity were 100% and 99%, respectively. MRI showed an alternative diagnosis in 41 of the 75 remaining patients. In 22 of the remaining 34 patients, a normal appendix was depicted with MRI. In two patients, where MRI showed no appendicitis, an alternative diagnosis or normal appendix, an unnecessary appendectomy was performed. The overall effect of using MRI in patients suspected of appendicitis on the use of hospital resources could have been a net saving between 55,746 euros and 72,534 euros. MRI has a high accuracy in detecting and excluding appendicitis, an alternative diagnosis or showing the normal appendix, and can be a valuable and cost-effective tool in the workup of patients clinically suspected of having appendicitis.

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Year:  2009        PMID: 19137303     DOI: 10.1007/s00330-008-1270-9

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


  32 in total

Review 1.  Suspected acute appendicitis: trends in management over 30 years.

Authors:  P F Jones
Journal:  Br J Surg       Date:  2001-12       Impact factor: 6.939

2.  Effect of ultrasonography and optional computed tomography on the outcome of appendectomy.

Authors:  A C van Breda Vriesman; B J Kole; J B C M Puylaert
Journal:  Eur Radiol       Date:  2003-07-05       Impact factor: 5.315

Review 3.  Computed tomography--an increasing source of radiation exposure.

Authors:  David J Brenner; Eric J Hall
Journal:  N Engl J Med       Date:  2007-11-29       Impact factor: 91.245

4.  Spiral CT: how much does radiation dose matter?

Authors:  A K Dixon; P Dendy
Journal:  Lancet       Date:  1998-10-03       Impact factor: 79.321

5.  Right-lower-quadrant pain and suspected appendicitis in pregnant women: evaluation with MR imaging--initial experience.

Authors:  Aytekin Oto; Randy D Ernst; Rajeev Shah; Mert Koroglu; Gregory Chaljub; Alfredo F Gei; Nikolaos Zacharias; George Saade
Journal:  Radiology       Date:  2004-12-10       Impact factor: 11.105

6.  Acute appendicitis in university students: a twenty-year study of 1,028 cases.

Authors:  P K Ferrier
Journal:  J Am Coll Health Assoc       Date:  1972-04

7.  Appendicitis. A critical review of diagnosis and treatment in 1,000 cases.

Authors:  F R Lewis; J W Holcroft; J Boey; E Dunphy
Journal:  Arch Surg       Date:  1975-05

8.  MR imaging of the normal appendix and acute appendicitis.

Authors:  Norihisa Nitta; Masashi Takahashi; Akira Furukawa; Kiyoshi Murata; Masayuki Mori; Masanobu Fukushima
Journal:  J Magn Reson Imaging       Date:  2005-02       Impact factor: 4.813

9.  The natural history of appendicitis in adults. A prospective study.

Authors:  C L Temple; S A Huchcroft; W J Temple
Journal:  Ann Surg       Date:  1995-03       Impact factor: 12.969

10.  MR imaging in children with nonperforated acute appendicitis: value of unenhanced MR imaging in sonographically selected cases.

Authors:  M Hörmann; K Paya; K Eibenberger; R Dorffner; S Lang; S Kreuzer; V M Metz
Journal:  AJR Am J Roentgenol       Date:  1998-08       Impact factor: 3.959

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  31 in total

1.  Utility of diffusion-weighted imaging in the diagnosis of acute appendicitis.

Authors:  Ercan Inci; Ozgur Kilickesmez; Elif Hocaoglu; Sibel Aydin; Sibel Bayramoglu; Tan Cimilli
Journal:  Eur Radiol       Date:  2010-10-06       Impact factor: 5.315

Review 2.  Emergency abdominal MRI: current uses and trends.

Authors:  Hei S Yu; Avneesh Gupta; Jorge A Soto; Christina LeBedis
Journal:  Br J Radiol       Date:  2015-11-19       Impact factor: 3.039

3.  Diagnostic performance of contrast-enhanced MR for acute appendicitis and alternative causes of abdominal pain in children.

Authors:  Jeffrey L Koning; John H Naheedy; Peter G Kruk
Journal:  Pediatr Radiol       Date:  2014-03-29

4.  Performance characteristics of magnetic resonance imaging without contrast agents or sedation in pediatric appendicitis.

Authors:  Ryne A Didier; Katharine L Hopkins; Fergus V Coakley; Sanjay Krishnaswami; David M Spiro; Bryan R Foster
Journal:  Pediatr Radiol       Date:  2017-06-19

5.  Trends in the Use of Medical Imaging to Diagnose Appendicitis at an Academic Medical Center.

Authors:  Michael D Repplinger; Andrew C Weber; Perry J Pickhardt; Victoria P Rajamanickam; James E Svenson; William J Ehlenbach; Ryan P Westergaard; Scott B Reeder; Elizabeth A Jacobs
Journal:  J Am Coll Radiol       Date:  2016-04-02       Impact factor: 5.532

6.  Imaging for appendicitis: should radiation-induced cancer risks affect modality selection?

Authors:  Sorapop Kiatpongsan; Lesley Meng; Jonathan D Eisenberg; Maurice Herring; Laura L Avery; Chung Yin Kong; Pari V Pandharipande
Journal:  Radiology       Date:  2014-07-01       Impact factor: 11.105

7.  Prospective evaluation of MRI compared with CT for the etiology of abdominal pain in emergency department patients with concern for appendicitis.

Authors:  John B Harringa; Rebecca L Bracken; John C Davis; Lu Mao; Douglas R Kitchin; Jessica B Robbins; Timothy J Ziemlewicz; Perry J Pickhardt; Scott B Reeder; Michael D Repplinger
Journal:  J Magn Reson Imaging       Date:  2019-03-20       Impact factor: 4.813

8.  Appendicitis-the balance between cost effectiveness and safety remains challenging.

Authors:  Juliane Liese; Thomas M Halbinger; Frank Ulrich; Wolf O Bechstein; Christoph W Strey
Journal:  Langenbecks Arch Surg       Date:  2014-03-16       Impact factor: 3.445

9.  Assessing 3D T2 FSE sequence for identification of the normal appendix: working toward a single-sequence MR appendicitis protocol.

Authors:  Nattinee Leelakanok; Andrew S Phelps; Matthew A Zapala; Kambrie Kato; Michael Ohliger; Yi Li; Jesse Courtier
Journal:  Emerg Radiol       Date:  2017-07-19

Review 10.  Improvement in the diagnosis of appendicitis.

Authors:  Frederick Thurston Drake; David Reed Flum
Journal:  Adv Surg       Date:  2013
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