Literature DB >> 19131267

Finite element analysis of stresses developed in the blood sac of a left ventricular assist device.

T L Haut Donahue1, W Dehlin, J Gillespie, W J Weiss, G Rosenberg.   

Abstract

The goal of this research is to develop a 3D finite element (FE) model of a left ventricular assist device (LVAD) to predict stresses in the blood sac. The hyperelastic stress-strain curves for the segmented poly(ether polyurethane urea) (SPEUU) blood sac were determined in both tension and compression using a servo-hydraulic testing system at various strain rates. Over the range of strain rates studied, the sac was not strain rate sensitive, however the material response was different for tension versus compression. The experimental tension and compression properties were used in a FE model that consisted of the pusher plate, blood sac and pump case. A quasi-static analysis was used to allow for nonlinearities due to contact and material deformation. The 3D FE model showed that blood sac stresses are not adversely affected by the location of the inlet and outlet ports of the device and that over the systolic ejection phase of the simulation the prediction of blood sac stresses from the full 3D model and an axisymmetric model are the same. Minimizing stresses in the blood sac will increase the longevity of the blood sac in vivo.

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Year:  2009        PMID: 19131267      PMCID: PMC2702508          DOI: 10.1016/j.medengphy.2008.11.011

Source DB:  PubMed          Journal:  Med Eng Phys        ISSN: 1350-4533            Impact factor:   2.242


  13 in total

Review 1.  Mechanical cardiac support 2000: current applications and future trial design. June 15-16, 2000 Bethesda, Maryland.

Authors:  L W Stevenson; R L Kormos; R C Bourge; A Gelijns; B P Griffith; R E Hershberger; S Hunt; J Kirklin; L W Miller; W E Pae; G Pantalos; D G Pennington; E A Rose; J T Watson; J T Willerson; J B Young; M L Barr; M R Costanzo; P Desvigne-Nickens; A M Feldman; O H Frazier; L Friedman; J D Hill; M A Konstam; P M McCarthy; R E Michler; M C Oz; B R Rosengard; W Sapirstein; R Shanker; C R Smith; R C Starling; D O Taylor; A Wichman
Journal:  J Am Coll Cardiol       Date:  2001-01       Impact factor: 24.094

2.  In vivo and in vitro stability of modified poly(urethaneurea) blood sacs.

Authors:  Q Liu; J Runt; G Felder; G Rosenberg; A J Snyder; W J Weiss; J Lewis; T Werley
Journal:  J Biomater Appl       Date:  2000-04       Impact factor: 2.646

3.  Finite element analysis of stresses developed in blood sacs of a pusherplate blood pump.

Authors:  Tammy L Haut Donahue; Gerson Rosenberg; C R Jacobs; William J Weiss
Journal:  Comput Methods Biomech Biomed Engin       Date:  2003-02       Impact factor: 1.763

4.  Adverse events in the use of HeartMate vented electric and Novacor left ventricular assist devices: comparing apples and oranges.

Authors:  Michael K Pasque; Joseph G Rogers
Journal:  J Thorac Cardiovasc Surg       Date:  2002-12       Impact factor: 5.209

5.  Fluid dynamic analysis of the 50 cc Penn State artificial heart under physiological operating conditions using particle image velocimetry.

Authors:  Pramote Hochareon; Keefe B Manning; Arnold A Fontaine; John M Tarbell; Steven Deutsch
Journal:  J Biomech Eng       Date:  2004-10       Impact factor: 2.097

6.  Development and validation of a computational fluid dynamics methodology for simulation of pulsatile left ventricular assist devices.

Authors:  Richard B Medvitz; James W Kreider; Keefe B Manning; Arnold A Fontaine; Steven Deutsch; Eric G Paterson
Journal:  ASAIO J       Date:  2007 Mar-Apr       Impact factor: 2.872

7.  Clinical experience with the Novacor ventricular assist system. Bridge to transplantation and the transition to permanent application.

Authors:  P M McCarthy; P M Portner; H G Tobler; V A Starnes; N Ramasamy; P E Oyer
Journal:  J Thorac Cardiovasc Surg       Date:  1991-10       Impact factor: 5.209

8.  Effect of strain and strain rate on fatigue-accelerated biodegradation of polyurethane.

Authors:  Michael J Wiggins; James M Anderson; Anne Hiltner
Journal:  J Biomed Mater Res A       Date:  2003-09-01       Impact factor: 4.396

9.  Initial experience with the AbioCor implantable replacement heart system.

Authors:  Robert D Dowling; Laman A Gray; Steven W Etoch; Hillel Laks; Daniel Marelli; Louis Samuels; John Entwistle; Greg Couper; Gus J Vlahakes; O H Frazier
Journal:  J Thorac Cardiovasc Surg       Date:  2004-01       Impact factor: 5.209

10.  A randomized study of the influence of perfusion technique and pH management strategy in 316 patients undergoing coronary artery bypass surgery. II. Neurologic and cognitive outcomes.

Authors:  J M Murkin; J S Martzke; A M Buchan; C Bentley; C J Wong
Journal:  J Thorac Cardiovasc Surg       Date:  1995-08       Impact factor: 5.209

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  3 in total

1.  Toward the Virtual Benchmarking of Pneumatic Ventricular Assist Devices: Application of a Novel Fluid-Structure Interaction-Based Strategy to the Penn State 12 cc Device.

Authors:  Alessandro Caimi; Francesco Sturla; Bryan Good; Marco Vidotto; Rachele De Ponti; Filippo Piatti; Keefe B Manning; Alberto Redaelli
Journal:  J Biomech Eng       Date:  2017-08-01       Impact factor: 2.097

Review 2.  Recent advances in computational methodology for simulation of mechanical circulatory assist devices.

Authors:  Alison L Marsden; Yuri Bazilevs; Christopher C Long; Marek Behr
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2014-01-21

3.  Investigating the Role of Interventricular Interdependence in Development of Right Heart Dysfunction During LVAD Support: A Patient-Specific Methods-Based Approach.

Authors:  Kevin L Sack; Yaghoub Dabiri; Thomas Franz; Scott D Solomon; Daniel Burkhoff; Julius M Guccione
Journal:  Front Physiol       Date:  2018-05-11       Impact factor: 4.566

  3 in total

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