Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Regulation and function of proinflammatory TH17 cells.

Literature DB >> 19076351

Regulation and function of proinflammatory TH17 cells.

Gustavo J Martinez¹, Roza I Nurieva, Xuexian O Yang, Chen Dong.

Abstract

Naïve CD4(+) helper T (TH) cells, upon activation by antigen-presenting cells (APC), differentiate into different types of effector cells that are characterized by their distinct cytokine production profiles and immune regulatory functions. In addition to TH1 and TH2 cells, a third subset of effector TH cells has recently been described and termed TH17. Since their identification, TH17 cells have emerged as crucial players in infectious, inflammatory, and autoimmune diseases, and cancer. In this review, we summarize the latest discoveries on the cytokine-mediated regulation and transcriptional programming of TH17 cells and their roles in different immune responses and diseases.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2008 PMID： 19076351 PMCID： PMC5793850 DOI： 10.1196/annals.1443.021

Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691

178 in total

1. Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

Authors: Kyle I Happel; Mingquan Zheng; Erana Young; Lee J Quinton; Euan Lockhart; Alistair J Ramsay; Judd E Shellito; Jill R Schurr; Gregory J Bagby; Steve Nelson; Jay K Kolls
Journal: J Immunol Date: 2003-05-01 Impact factor: 5.422

2. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

Authors: Ingunn M Stromnes; Lauren M Cerretti; Denny Liggitt; Robert A Harris; Joan M Goverman
Journal: Nat Med Date: 2008-02-17 Impact factor: 53.440

3. Understanding the IL-23-IL-17 immune pathway.

Authors: Brent S McKenzie; Robert A Kastelein; Daniel J Cua
Journal: Trends Immunol Date: 2005-11-14 Impact factor: 16.687

4. A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells.

Authors: Roberta Caruso; Daniele Fina; Ilaria Peluso; Carmine Stolfi; Massimo Claudio Fantini; Valentina Gioia; Flavio Caprioli; Giovanna Del Vecchio Blanco; Omero Alessandro Paoluzi; Thomas T Macdonald; Francesco Pallone; Giovanni Monteleone
Journal: Gastroenterology Date: 2006-10-01 Impact factor: 22.682

5. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis.

Authors: Yutaka Komiyama; Susumu Nakae; Taizo Matsuki; Aya Nambu; Harumichi Ishigame; Shigeru Kakuta; Katsuko Sudo; Yoichiro Iwakura
Journal: J Immunol Date: 2006-07-01 Impact factor: 5.422

6. T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation.

Authors: Ming O Li; Yisong Y Wan; Richard A Flavell
Journal: Immunity Date: 2007-05-03 Impact factor: 31.745

7. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.

Authors: Daniel Mucida; Yunji Park; Gisen Kim; Olga Turovskaya; Iain Scott; Mitchell Kronenberg; Hilde Cheroutre
Journal: Science Date: 2007-06-14 Impact factor: 47.728

8. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

Authors: Caroline Sutton; Corinna Brereton; Brian Keogh; Kingston H G Mills; Ed C Lavelle
Journal: J Exp Med Date: 2006-07-03 Impact factor: 14.307

9. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function.

Authors: Liang Zhou; Jared E Lopes; Mark M W Chong; Ivaylo I Ivanov; Roy Min; Gabriel D Victora; Yuelei Shen; Jianguang Du; Yuri P Rubtsov; Alexander Y Rudensky; Steven F Ziegler; Dan R Littman
Journal: Nature Date: 2008-03-26 Impact factor: 49.962

10. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation.

Authors: Craig A Murphy; Claire L Langrish; Yi Chen; Wendy Blumenschein; Terrill McClanahan; Robert A Kastelein; Jonathon D Sedgwick; Daniel J Cua
Journal: J Exp Med Date: 2003-12-08 Impact factor: 14.307

69 in total

1. The E3 ubiquitin ligase adaptor Ndfip1 regulates Th17 differentiation by limiting the production of proinflammatory cytokines.

Authors: Hilda E Ramon; Allison M Beal; Yuhong Liu; George Scott Worthen; Paula M Oliver
Journal: J Immunol Date: 2012-03-07 Impact factor: 5.422

Review 2. Highlights of the advances in basic immunology in 2011.

Authors: Juan Liu; Shuxun Liu; Xuetao Cao
Journal: Cell Mol Immunol Date: 2012-04-23 Impact factor: 11.530

Review 3. IL-17 family member cytokines: regulation and function in innate immunity.

Authors: Joseph M Reynolds; Pornpimon Angkasekwinai; Chen Dong
Journal: Cytokine Growth Factor Rev Date: 2010-11-11 Impact factor: 7.638

4. Immunological cell type characterization and Th1-Th17 cytokine production in a mouse model of Gaucher disease.

Authors: Manoj Kumar Pandey; Reena Rani; Wujuan Zhang; Kenneth Setchell; Gregory A Grabowski
Journal: Mol Genet Metab Date: 2012-04-30 Impact factor: 4.797

5. Prolonged ovalbumin challenge facilitates Th17 polarization in sensitized mice.

Authors: Qing Wang; Hequan Li; Zhiyuan Zhang; Yinan Yao; Jianying Zhou
Journal: Inflamm Res Date: 2010-02-14 Impact factor: 4.575

6. Cell-intrinsic role for IFN-α-STAT1 signals in regulating murine Peyer patch plasmacytoid dendritic cells and conditioning an inflammatory response.

Authors: Haiyan S Li; Alexander Gelbard; Gustavo J Martinez; Eiji Esashi; Huiyuan Zhang; Hoainam Nguyen-Jackson; Yong-Jun Liu; Willem W Overwijk; Stephanie S Watowich
Journal: Blood Date: 2011-08-09 Impact factor: 22.113

7. Critical role for IL-17A/F in the immunopathogenesis of obliterative airway disease induced by Anti-MHC I antibodies.

Authors: Haseeb Ilias Basha; Sabarinathan Ramachandran; Venkataswarup Tiriveedhi; Masashi Takenaka; Vijay Subramanian; Dilip S Nath; Nicholas Benshoff; G Alec Patterson; Thalachallour Mohanakumar
Journal: Transplantation Date: 2013-01-27 Impact factor: 4.939