| Literature DB >> 21074482 |
Joseph M Reynolds1, Pornpimon Angkasekwinai, Chen Dong.
Abstract
Recently, the IL-17 family member cytokines have become prominent subjects of investigation. IL-17 (IL-17A) is the best-described member of this family where its production has been mainly attributed to a specialized T helper subset of the adaptive immune response termed Th17. However, recent research on this and other Th17 cytokines has revealed new sources and functions of IL-17 family members in the innate immune response. This review will highlight recent advances in the field of IL-17 family member cytokines and will predominantly focus on the innate regulation and function of IL-17, IL-17F, and IL-25.Entities:
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Year: 2010 PMID: 21074482 PMCID: PMC3008409 DOI: 10.1016/j.cytogfr.2010.10.002
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN: 1359-6101 Impact factor: 7.638