Literature DB >> 19074499

CNTRICS final task selection: control of attention.

Keith H Nuechterlein1, Steven J Luck, Cindy Lustig, Martin Sarter.   

Abstract

The construct of attention has many facets that have been examined in human and animal research and in healthy and psychiatrically disordered conditions. The Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) group concluded that control of attention-the processes that guide selection of task-relevant inputs-is particularly impaired in schizophrenia and could profit from further work with refined measurement tools. Thus, nominations for cognitive tasks that provide discrete measures of control of attention were sought and were then evaluated at the third CNTRICS meeting for their promise for future use in treatment development. This article describes the 5 nominated measures and their strengths and weaknesses for cognitive neuroscience work relevant to treatment development. Two paradigms, Guided Search and the Distractor Condition Sustained Attention Task, were viewed as having the greatest immediate promise for development into tools for treatment research in schizophrenia and are described in more detail by their nominators.

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Mesh:

Year:  2009        PMID: 19074499      PMCID: PMC2617743          DOI: 10.1093/schbul/sbn158

Source DB:  PubMed          Journal:  Schizophr Bull        ISSN: 0586-7614            Impact factor:   9.306


  75 in total

1.  Selective impairment of attentional networks of orienting and executive control in schizophrenia.

Authors:  Kai Wang; Jin Fan; Yi Dong; Chang-Qing Wang; Tatia M C Lee; Michael I Posner
Journal:  Schizophr Res       Date:  2005-10-15       Impact factor: 4.939

2.  Impaired control of visual attention in schizophrenia.

Authors:  Rebecca L Fuller; Steven J Luck; Elsie L Braun; Benjamin M Robinson; Robert P McMahon; James M Gold
Journal:  J Abnorm Psychol       Date:  2006-05

3.  Just say no: how are visual searches terminated when there is no target present?

Authors:  M M Chun; J M Wolfe
Journal:  Cogn Psychol       Date:  1996-02       Impact factor: 3.468

4.  Responses of neurons in inferior temporal cortex during memory-guided visual search.

Authors:  L Chelazzi; J Duncan; E K Miller; R Desimone
Journal:  J Neurophysiol       Date:  1998-12       Impact factor: 2.714

5.  Augmented prefrontal acetylcholine release during challenged attentional performance.

Authors:  Rouba Kozak; John P Bruno; Martin Sarter
Journal:  Cereb Cortex       Date:  2005-03-23       Impact factor: 5.357

Review 6.  Identification of separable cognitive factors in schizophrenia.

Authors:  Keith H Nuechterlein; Deanna M Barch; James M Gold; Terry E Goldberg; Michael F Green; Robert K Heaton
Journal:  Schizophr Res       Date:  2004-12-15       Impact factor: 4.939

7.  Prefrontal acetylcholine release controls cue detection on multiple timescales.

Authors:  Vinay Parikh; Rouba Kozak; Vicente Martinez; Martin Sarter
Journal:  Neuron       Date:  2007-10-04       Impact factor: 17.173

8.  Developmental Processes in Schizophrenic Disorders: longitudinal studies of vulnerability and stress.

Authors:  K H Nuechterlein; M E Dawson; M Gitlin; J Ventura; M J Goldstein; K S Snyder; C M Yee; J Mintz
Journal:  Schizophr Bull       Date:  1992       Impact factor: 9.306

9.  Neural basis of saccade target selection in frontal eye field during visual search.

Authors:  J D Schall; D P Hanes
Journal:  Nature       Date:  1993-12-02       Impact factor: 49.962

10.  Behavioral vigilance in rats: task validation and effects of age, amphetamine, and benzodiazepine receptor ligands.

Authors:  J McGaughy; M Sarter
Journal:  Psychopharmacology (Berl)       Date:  1995-02       Impact factor: 4.530

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  48 in total

1.  Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine.

Authors:  Kathleen S Alexander; Hui-Qiu Wu; Robert Schwarcz; John P Bruno
Journal:  Psychopharmacology (Berl)       Date:  2011-10-26       Impact factor: 4.530

Review 2.  CNTRICS final animal model task selection: control of attention.

Authors:  C Lustig; R Kozak; M Sarter; J W Young; T W Robbins
Journal:  Neurosci Biobehav Rev       Date:  2012-06-06       Impact factor: 8.989

Review 3.  Evaluation of the clinical efficacy of asenapine in schizophrenia.

Authors:  Arpi Minassian; Jared W Young
Journal:  Expert Opin Pharmacother       Date:  2010-08       Impact factor: 3.889

Review 4.  Advancing schizophrenia drug discovery: optimizing rodent models to bridge the translational gap.

Authors:  Judith Pratt; Catherine Winchester; Neil Dawson; Brian Morris
Journal:  Nat Rev Drug Discov       Date:  2012-06-22       Impact factor: 84.694

5.  Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits.

Authors:  Giovanna Paolone; Caitlin S Mallory; Ajeesh Koshy Cherian; Thomas R Miller; Randy D Blakely; Martin Sarter
Journal:  Neuropharmacology       Date:  2013-08-16       Impact factor: 5.250

6.  Transient inactivation of the neonatal ventral hippocampus permanently disrupts the mesolimbic regulation of prefrontal cholinergic transmission: implications for schizophrenia.

Authors:  Julie M Brooks; Martin Sarter; John P Bruno
Journal:  Neuropsychopharmacology       Date:  2011-08-03       Impact factor: 7.853

7.  Sustained attention in mice: expanding the translational utility of the SAT by incorporating the Michigan Controlled Access Response Port (MICARP).

Authors:  Megan St Peters; Ajeesh Koshy Cherian; Marc Bradshaw; Martin Sarter
Journal:  Behav Brain Res       Date:  2011-08-22       Impact factor: 3.332

8.  Harnessing cognitive neuroscience to develop new treatments for improving cognition in schizophrenia: CNTRICS selected cognitive paradigms for animal models.

Authors:  Holly Moore; Mark A Geyer; Cameron S Carter; Deanna M Barch
Journal:  Neurosci Biobehav Rev       Date:  2013-09-30       Impact factor: 8.989

9.  The effect of distracting noise on the neuronal mechanisms of attention in schizophrenia.

Authors:  Jason R Tregellas; Jason Smucny; Lindsay Eichman; Donald C Rojas
Journal:  Schizophr Res       Date:  2012-10-09       Impact factor: 4.939

10.  Disruption of mesolimbic regulation of prefrontal cholinergic transmission in an animal model of schizophrenia and normalization by chronic clozapine treatment.

Authors:  Kathleen S Alexander; Julie M Brooks; Martin Sarter; John P Bruno
Journal:  Neuropsychopharmacology       Date:  2009-08-19       Impact factor: 7.853

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