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Literature DB >> 19067551

Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras.

Abhisek Banerjee¹, Eduard Sergienko, Stefan Vasile, Vineet Gupta, Kristiina Vuori, Peter Wipf.

Abstract

An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19067551 PMCID： PMC4257705 DOI： 10.1021/ol802247m

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

27 in total

Review 1. Non peptidic alphavbeta3 antagonists: recent developments.

Authors: Barbara Cacciari; Giampiero Spalluto
Journal: Curr Med Chem Date: 2005 Impact factor: 4.530

2. Expedient synthesis and design strategies for new peptoid construction.

Authors: Benjamin C Gorske; Sarah A Jewell; Emily J Guerard; Helen E Blackwell
Journal: Org Lett Date: 2005-04-14 Impact factor: 6.005

3. The "triamino-analogue" of methyl allocholate; a rigid, functionalised scaffold for supramolecular chemistry.

Authors: Khadga M Bhattarai; Vicente del Amo; Germinal Magro; Adam L Sisson; Jean-Baptiste Joos; Jonathan P H Charmant; Anob Kantacha; Anthony P Davis
Journal: Chem Commun (Camb) Date: 2006-05-15 Impact factor: 6.222

4. Parallel synthesis of peptide libraries using microwave irradiation.

Authors: Justin K Murray; Samuel H Gellman
Journal: Nat Protoc Date: 2007 Impact factor: 13.491

5. Rapid solid-phase synthesis of a calmodulin-binding peptide using controlled microwave irradiation.

Authors: Bernadett Bacsa; C Oliver Kappe
Journal: Nat Protoc Date: 2007 Impact factor: 13.491

6. Evaluation of a two-stage screening procedure in the combinatorial search for serine protease-like activity.

Authors: Annemieke Madder; Liu Li; Hilde De Muynck; Nadia Farcy; Dirk Van Haver; Franky Fant; Gerd Vanhoenacker; Pat Sandra; Anthony P Davis; Pierre J De Clercq
Journal: J Comb Chem Date: 2002 Nov-Dec

7. Limiting racemization and aspartimide formation in microwave-enhanced Fmoc solid phase peptide synthesis.

Authors: Stacey A Palasek; Zachary J Cox; Jonathan M Collins
Journal: J Pept Sci Date: 2007-03 Impact factor: 1.905

8. A new spiroketal steroid from Gorgonella umbraculum.

Authors: Ammanamanchi S R Anjaneyulu; Vadali Lakshmana Rao; Vedula Girija Sastry
Journal: Nat Prod Res Date: 2003-06 Impact factor: 2.861

9. Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics.

Authors: Luca Gentilucci; Giuliana Cardillo; Federico Squassabia; Alessandra Tolomelli; Santi Spampinato; Antonino Sparta; Monica Baiula
Journal: Bioorg Med Chem Lett Date: 2007-01-27 Impact factor: 2.823

Review 10. Peptidomimetics - antagonists of the fibrinogen receptors: molecular design, structures, properties and therapeutic applications.

Authors: S A Andronati; T L Karaseva; A A Krysko
Journal: Curr Med Chem Date: 2004-05 Impact factor: 4.530

5 in total

1. Peptide-Like Molecules (PLMs): A Journey from Peptide Bond Isosteres to Gramicidin S Mimetics and Mitochondrial Targeting Agents.

Authors: Peter Wipf; Jingbo Xiao; Corey R J Stephenson
Journal: Chimia (Aarau) Date: 2009-11 Impact factor: 1.509