| Literature DB >> 1906694 |
B Giwercman1, E T Jensen, N Høiby, A Kharazmi, J W Costerton.
Abstract
Imipenem induced high levels of beta-lactamase production in Pseudomonas aeruginosa biofilms. Piperacillin also induced beta-lactamase production in these biofilms but to a lesser degree. The combination of beta-lactamase production with other protective properties of the biofilm mode of growth could be a major reason for the persistence of this sessile bacterium in chronic infections.Entities:
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Year: 1991 PMID: 1906694 PMCID: PMC245148 DOI: 10.1128/AAC.35.5.1008
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191