| Literature DB >> 1503455 |
H Anwar1, J L Strap, J W Costerton.
Abstract
Planktonic and young biofilm cells were completely eradicated after exposure of these cells to drug levels representing one loading and two maintenance doses of tobramycin and cephalexin. A very different picture was observed when antibiotic exposure was initiated on day 21. Complete eradication of the old biofilm cells was not observed even when the antibiotic exposure was continued for an extra 6 days. Regrowth of the organism was observed when the antibiotic exposure was terminated.Entities:
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Year: 1992 PMID: 1503455 PMCID: PMC189482 DOI: 10.1128/AAC.36.4.890
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191