Literature DB >> 19063666

Effects of electric field stress on a beta-amyloid peptide.

Francesca Toschi1, Francesca Lugli, Fabio Biscarini, Francesco Zerbetto.   

Abstract

The interaction of beta-amyloid (Abeta) peptides with externally applied electric fields (EF) of varying strengths was investigated by means of molecular dynamics (MD) simulations. The results suggest that the EF favors the switch of Abeta-peptides from helical to beta-sheet conformation, and a mechanism is tentatively proposed. Switching off the field does not restore the original conformation.

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Year:  2009        PMID： 19063666     DOI： 10.1021/jp807896g

Source DB:  PubMed          Journal:  J Phys Chem B        ISSN： 1520-5207            Impact factor:   2.991


  14 in total

1.  Electric field-driven disruption of a native beta-sheet protein conformation and generation of a helix-structure.

Authors:  Pedro Ojeda-May; Martin E Garcia
Journal:  Biophys J       Date:  2010-07-21       Impact factor: 4.033

2.  True and apparent inhibition of amyloid fibril formation.

Authors:  Pedro M Martins
Journal:  Prion       Date:  2012-12-11       Impact factor: 3.931

3.  Potential-assisted adsorption of bovine serum albumin onto optically transparent carbon electrodes.

Authors:  Tomás E Benavidez; Carlos D Garcia
Journal:  Langmuir       Date:  2013-11-08       Impact factor: 3.882

4.  Off-axis electron holography of bacterial cells and magnetic nanoparticles in liquid.

Authors:  Tanya Prozorov; Trevor P Almeida; András Kovács; Rafal E Dunin-Borkowski
Journal:  J R Soc Interface       Date:  2017-10       Impact factor: 4.118

Review 5.  Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.

Authors:  Phuong H Nguyen; Ayyalusamy Ramamoorthy; Bikash R Sahoo; Jie Zheng; Peter Faller; John E Straub; Laura Dominguez; Joan-Emma Shea; Nikolay V Dokholyan; Alfonso De Simone; Buyong Ma; Ruth Nussinov; Saeed Najafi; Son Tung Ngo; Antoine Loquet; Mara Chiricotto; Pritam Ganguly; James McCarty; Mai Suan Li; Carol Hall; Yiming Wang; Yifat Miller; Simone Melchionna; Birgit Habenstein; Stepan Timr; Jiaxing Chen; Brianna Hnath; Birgit Strodel; Rakez Kayed; Sylvain Lesné; Guanghong Wei; Fabio Sterpone; Andrew J Doig; Philippe Derreumaux
Journal:  Chem Rev       Date:  2021-02-05       Impact factor: 60.622

6.  Insight into the stability of cross-β amyloid fibril from VEALYL short peptide with molecular dynamics simulation.

Authors:  Wei Ye; Yue Chen; Wei Wang; Qingfen Yu; Yixue Li; Jian Zhang; Hai-Feng Chen
Journal:  PLoS One       Date:  2012-05-10       Impact factor: 3.240

7.  Tubulin response to intense nanosecond-scale electric field in molecular dynamics simulation.

Authors:  Paolo Marracino; Daniel Havelka; Jiří Průša; Micaela Liberti; Jack Tuszynski; Ahmed T Ayoub; Francesca Apollonio; Michal Cifra
Journal:  Sci Rep       Date:  2019-07-19       Impact factor: 4.379

8.  Nanosecond pulsed electric signals can affect electrostatic environment of proteins below the threshold of conformational effects: The case study of SOD1 with a molecular simulation study.

Authors:  Elena Della Valle; Paolo Marracino; Olga Pakhomova; Micaela Liberti; Francesca Apollonio
Journal:  PLoS One       Date:  2019-08-27       Impact factor: 3.240

9.  Molecular dynamics simulation of the nanosecond pulsed electric field effect on kinesin nanomotor.

Authors:  Jiří Průša; Michal Cifra
Journal:  Sci Rep       Date:  2019-12-23       Impact factor: 4.379

10.  Can electromagnetic fields influence the structure and enzymatic digest of proteins? A critical evaluation of microwave-assisted proteomics protocols.

Authors:  Markus Damm; Christoph Nusshold; David Cantillo; Gerald N Rechberger; Karl Gruber; Wolfgang Sattler; C Oliver Kappe
Journal:  J Proteomics       Date:  2012-08-06       Impact factor: 4.044
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