Literature DB >> 20643079

Electric field-driven disruption of a native beta-sheet protein conformation and generation of a helix-structure.

Pedro Ojeda-May1, Martin E Garcia.   

Abstract

We demonstrate that an external constant electric field is able to modify the secondary structure of a protein and induce a transition from a beta-sheet into a helix-like conformation. This dramatic change is driven by a global rearrangement of the dipole moments at the amide planes. We also predict electric-field-induced modifications of the intermediate states of the protein. Copyright (c) 2010 Biophysical Society. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20643079      PMCID： PMC2905109          DOI： 10.1016/j.bpj.2010.04.040

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


  18 in total

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2.  Diffraction and imaging from a beam of laser-aligned proteins: resolution limits.

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3.  Protein flexibility: multiple molecular dynamics simulations of insulin chain B.

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4.  Retention of nativelike conformation by proteins embedded in high external electric fields.

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Journal:  J Chem Phys       Date:  2005-05-08       Impact factor: 3.488

5.  Effective potentials for folding proteins.

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Journal:  Phys Rev Lett       Date:  2006-02-22       Impact factor: 9.161

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7.  Energetics of the dipole flip-flop motion in a ferroelectric polymer chain.

Authors:  Lei Cai; Xuewen Wang; Yesim Darici; Jiandi Zhang; P A Dowben
Journal:  J Chem Phys       Date:  2007-03-28       Impact factor: 3.488

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Journal:  Curr Opin Struct Biol       Date:  1998-02       Impact factor: 6.809

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10.  Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers.

Authors:  Juha Laurén; David A Gimbel; Haakon B Nygaard; John W Gilbert; Stephen M Strittmatter
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  12 in total

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Journal:  J Biol Phys       Date:  2014-03-25       Impact factor: 1.365

Review 3.  Aerodynamics and the role of the earth's electric field in the spiders' ballooning flight.

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5.  Tubulin's response to external electric fields by molecular dynamics simulations.

Authors:  Joshua J Timmons; Jordane Preto; Jack A Tuszynski; Eric T Wong
Journal:  PLoS One       Date:  2018-09-19       Impact factor: 3.240

6.  Tubulin response to intense nanosecond-scale electric field in molecular dynamics simulation.

Authors:  Paolo Marracino; Daniel Havelka; Jiří Průša; Micaela Liberti; Jack Tuszynski; Ahmed T Ayoub; Francesca Apollonio; Michal Cifra
Journal:  Sci Rep       Date:  2019-07-19       Impact factor: 4.379

7.  Nanosecond pulsed electric signals can affect electrostatic environment of proteins below the threshold of conformational effects: The case study of SOD1 with a molecular simulation study.

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Journal:  PLoS One       Date:  2019-08-27       Impact factor: 3.240

8.  Molecular dynamics simulation of the nanosecond pulsed electric field effect on kinesin nanomotor.

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Journal:  Sci Rep       Date:  2019-12-23       Impact factor: 4.379

9.  Electro-opening of a microtubule lattice in silico.

Authors:  Jiří Průša; Ahmed Taha Ayoub; Djamel Eddine Chafai; Daniel Havelka; Michal Cifra
Journal:  Comput Struct Biotechnol J       Date:  2021-03-04       Impact factor: 7.271

10.  Modulation of Peptide Based Nano-Assemblies with Electric and Magnetic Fields.

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Journal:  Sci Rep       Date:  2017-06-02       Impact factor: 4.379
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