Literature DB >> 19062007

Treatment of obesity in polycystic ovary syndrome: a position statement of the Androgen Excess and Polycystic Ovary Syndrome Society.

Lisa J Moran1, Renato Pasquali, Helena J Teede, Kathleen M Hoeger, Robert J Norman.   

Abstract

OBJECTIVE: To summarize current evidence on lifestyle management (dietary, exercise, or behavioral interventions) of obesity in women with polycystic ovary syndrome (PCOS), to indicate gaps in knowledge, and to review the medical and surgical alternatives for weight management.
DESIGN: Expert panel appointed by the Androgen Excess and PCOS Society (AEPCOS Society) to review the literature and draft the initial report after a consensus process via electronic communication. The initial report was reviewed and critiqued by all expert panel members and the AEPCOS Society Board of Directors and modified based on their comments. CONCLUSION(S): Lifestyle management should be used as the primary therapy in overweight and obese women with PCOS for the treatment of metabolic complications. For reproductive abnormalities, lifestyle modification may improve ovulatory function and pregnancy. Data are preliminary for improvement in pregnancy and live-birth rates, and further research is needed. There is currently no evidence that modifying dietary macronutrient composition offers additional benefits over conventional dietary approaches for weight loss, and further research is needed. Emerging evidence suggests that exercise offers additional benefits to dietary energy restriction for reproductive features of PCOS.

Entities:  

Mesh:

Year:  2008        PMID: 19062007     DOI: 10.1016/j.fertnstert.2008.09.018

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  87 in total

Review 1.  Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome.

Authors:  Selma F Witchel; Sergio E Recabarren; Frank González; Evanthia Diamanti-Kandarakis; Kai I Cheang; Antoni J Duleba; Richard S Legro; Roy Homburg; Renato Pasquali; Rogerio A Lobo; Christos C Zouboulis; Fahrettin Kelestimur; Franca Fruzzetti; Walter Futterweit; Robert J Norman; David H Abbott
Journal:  Endocrine       Date:  2012-06-04       Impact factor: 3.633

2.  Effect of meal frequency on glucose and insulin levels in women with polycystic ovary syndrome: a randomised trial.

Authors:  E Papakonstantinou; I Kechribari; P Mitrou; E Trakakis; D Vassiliadi; E Georgousopoulou; A Zampelas; M D Kontogianni; G Dimitriadis
Journal:  Eur J Clin Nutr       Date:  2016-02-10       Impact factor: 4.016

3.  Patterns of Bariatric Surgeries Among U.S. Women Diagnosed with Polycystic Ovarian Syndrome.

Authors:  Hind A Beydoun; May A Beydoun; Sharmin Hossain; Laurel Stadtmauer; Shaker M Eid; Alan B Zonderman
Journal:  J Womens Health (Larchmt)       Date:  2020-02-20       Impact factor: 2.681

4.  Habitual physical activity is associated with improved anthropometric and androgenic profile in PCOS: a cross-sectional study.

Authors:  F M Mario; S K Graff; P M Spritzer
Journal:  J Endocrinol Invest       Date:  2016-10-22       Impact factor: 4.256

Review 5.  Optimizing reproductive health in women with obesity and infertility.

Authors:  Matea Belan; Soren Harnois-Leblanc; Blandine Laferrère; Jean-Patrice Baillargeon
Journal:  CMAJ       Date:  2018-06-18       Impact factor: 8.262

6.  Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: a pilot randomized double-blind study.

Authors:  Gwinnett Ladson; William C Dodson; Stephanie D Sweet; Anthony E Archibong; Allen R Kunselman; Laurence M Demers; Peter A Lee; Nancy I Williams; Ponjola Coney; Richard S Legro
Journal:  Fertil Steril       Date:  2011-06-30       Impact factor: 7.329

Review 7.  Adverse effects of the common treatments for polycystic ovary syndrome: a systematic review and meta-analysis.

Authors:  Juan Pablo Domecq; Gabriela Prutsky; Rebecca J Mullan; Vishnu Sundaresh; Amy T Wang; Patricia J Erwin; Corrine Welt; David Ehrmann; Victor M Montori; Mohammad Hassan Murad
Journal:  J Clin Endocrinol Metab       Date:  2013-10-03       Impact factor: 5.958

8.  Developmental programming: impact of prenatal testosterone excess and postnatal weight gain on insulin sensitivity index and transfer of traits to offspring of overweight females.

Authors:  V Padmanabhan; A Veiga-Lopez; D H Abbott; S E Recabarren; C Herkimer
Journal:  Endocrinology       Date:  2009-12-04       Impact factor: 4.736

Review 9.  Endocrine changes (beyond diabetes) after bariatric surgery in adult life.

Authors:  S Savastano; C Di Somma; R Pivonello; G Tarantino; F Orio; V Nedi; A Colao
Journal:  J Endocrinol Invest       Date:  2013-02-27       Impact factor: 4.256

Review 10.  Genetics of the polycystic ovary syndrome.

Authors:  Gülüm Kosova; Margrit Urbanek
Journal:  Mol Cell Endocrinol       Date:  2012-10-16       Impact factor: 4.102

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