F M Mario1,2, S K Graff1, P M Spritzer3,4. 1. Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, 90035-003, Brazil. 2. Federal Institute of Education, Science and Technology of Rio Grande do Sul, Porto Alegre, 90030-041, Brazil. 3. Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350, Porto Alegre, RS, 90035-003, Brazil. spritzer@ufrgs.br. 4. Laboratory of Molecular Endocrinology, Department of Physiology, Federal University of Rio Grande do Sul, Porto Alegre, 90035-003, Brazil. spritzer@ufrgs.br.
Abstract
PURPOSE: To examine the effect of habitual physical activity (PA) on the metabolic and hormonal profiles of women with polycystic ovary syndrome. MATERIALS AND METHODS: Anthropometric, metabolic and hormonal assessment and determination of habitual PA levels with a digital pedometer were evaluated in 84 women with PCOS and 67 age- and body mass index (BMI)-matched controls. PA status was defined according to number of steps (≥7500 steps, active, or <7500 steps, sedentary). RESULTS: BMI was lower in active women from both groups. Active PCOS women presented lower waist circumference (WC) and lipid accumulation product (LAP) values versus sedentary PCOS women. In the control group, active women also had lower WC, lower values for fasting and 120-min insulin, and lower LAP than sedentary controls. In the PCOS group, androgen levels were lower in active versus sedentary women (p = 0.001). In the control group, free androgen index (FAI) was also lower in active versus sedentary women (p = 0.018). Homeostasis model assessment of insulin resistance and 2000 daily step increments were independent predictors of FAI. Each 2000 daily step increment was associated with a decrease of 1.07 in FAI. CONCLUSIONS: Habitual PA was associated with a better anthropometric and androgenic profile in PCOS.
PURPOSE: To examine the effect of habitual physical activity (PA) on the metabolic and hormonal profiles of women with polycystic ovary syndrome. MATERIALS AND METHODS: Anthropometric, metabolic and hormonal assessment and determination of habitual PA levels with a digital pedometer were evaluated in 84 women with PCOS and 67 age- and body mass index (BMI)-matched controls. PA status was defined according to number of steps (≥7500 steps, active, or <7500 steps, sedentary). RESULTS: BMI was lower in active women from both groups. Active PCOS women presented lower waist circumference (WC) and lipid accumulation product (LAP) values versus sedentary PCOS women. In the control group, active women also had lower WC, lower values for fasting and 120-min insulin, and lower LAP than sedentary controls. In the PCOS group, androgen levels were lower in active versus sedentary women (p = 0.001). In the control group, free androgen index (FAI) was also lower in active versus sedentary women (p = 0.018). Homeostasis model assessment of insulin resistance and 2000 daily step increments were independent predictors of FAI. Each 2000 daily step increment was associated with a decrease of 1.07 in FAI. CONCLUSIONS: Habitual PA was associated with a better anthropometric and androgenic profile in PCOS.
Authors: Maria Kravariti; Katerina K Naka; Sophia N Kalantaridou; Nikolaos Kazakos; Christos S Katsouras; Antonis Makrigiannakis; Evangelos A Paraskevaidis; George P Chrousos; Agathocles Tsatsoulis; Lampros K Michalis Journal: J Clin Endocrinol Metab Date: 2005-06-28 Impact factor: 5.958
Authors: Nigel K Stepto; Samantha Cassar; Anju E Joham; Samantha K Hutchison; Cheryce L Harrison; Rebecca F Goldstein; Helena J Teede Journal: Hum Reprod Date: 2013-01-12 Impact factor: 6.918
Authors: Bart C J M Fauser; Basil C Tarlatzis; Robert W Rebar; Richard S Legro; Adam H Balen; Roger Lobo; Enrico Carmina; Jeffrey Chang; Bulent O Yildiz; Joop S E Laven; Jacky Boivin; Felice Petraglia; C N Wijeyeratne; Robert J Norman; Andrea Dunaif; Stephen Franks; Robert A Wild; Daniel Dumesic; Kurt Barnhart Journal: Fertil Steril Date: 2011-12-06 Impact factor: 7.329
Authors: R A Condorelli; A E Calogero; M Di Mauro; L M Mongioi'; R Cannarella; G Rosta; S La Vignera Journal: J Endocrinol Invest Date: 2017-09-23 Impact factor: 4.256
Authors: A D Genazzani; K Shefer; D Della Casa; A Prati; A Napolitano; A Manzo; G Despini; T Simoncini Journal: J Endocrinol Invest Date: 2017-10-31 Impact factor: 4.256
Authors: Ana L Rocha; Flávia R Oliveira; Rosana C Azevedo; Virginia A Silva; Thais M Peres; Ana L Candido; Karina B Gomes; Fernando M Reis Journal: F1000Res Date: 2019-04-26
Authors: Annie W Lin; Maryam Kazemi; Brittany Y Jarrett; Heidi Vanden Brink; Kathleen M Hoeger; Steven D Spandorfer; Marla E Lujan Journal: Nutrients Date: 2019-11-08 Impact factor: 5.717