Literature DB >> 19054639

Low dose multi-detector CT of the chest (iLEAD Study): visual ranking of different simulated mAs levels.

Julia Ley-Zaporozhan1, Sebastian Ley, Frank Krummenauer, Yoshiharu Ohno, Hiroto Hatabu, Hans-Ulrich Kauczor.   

Abstract

PURPOSE: Detailed evaluation of the lung parenchyma might be impaired by use of low dose CT as image noise increases and subsequently image quality decreases. The aim of our study was to determine the accuracy of visual perception of differences in image quality and noise at low dose chest CT.
MATERIALS AND METHODS: Forty-four patients suffering from emphysema underwent CT (Aquilion-16, 120kV, 150mAs, 1mm-collimation). Original raw data were used for simulation of 10 different mAs settings from 10mAs to 100mAs in 10mAs increments. Three representative hard copy images (carina, 4cm above, 5cm below) were printed for evaluation of lung parenchyma (high-resolution kernel, lung window) and mediastinum (soft-kernel, soft tissue window). Ranking of expected low mAs level was performed for lung and soft tissue separately based on visual perception by three-blinded chest radiologist independently. Results were compared to the real simulated mAs.
RESULTS: The accuracy for correct ranking of the original 150mAs scan was 89% for lung and 86% for soft tissue while it was 99% for the simulated 10mAs for both windows. In comparison to the lowest mAs a significant error increase was found for the lung at 60-100mAs (with error increase of 30-47%) for reader-I; 60-100mAs for (33-64%) for reader-II and 70-100mAs (38-57%) for reader-III. For the soft tissue: 60-150mAs (with error increase of 28-63%) for reader-I; 50-100mAs (35-56%) for reader-II and 50-90mAs (35-40%) for reader-III.
CONCLUSION: Simulated dose levels below 60mAs (=42mAs(eff)) were clearly differentiated from higher dose levels by all readers. Therefore, imaging doses could be lowered down to 60mAs without a diagnostically relevant increase in noise impairing image quality. Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved.

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Year:  2008        PMID: 19054639     DOI: 10.1016/j.ejrad.2008.10.006

Source DB:  PubMed          Journal:  Eur J Radiol        ISSN: 0720-048X            Impact factor:   3.528


  4 in total

Review 1.  [HRCT technique with low-dose protocols for interstitial lung diseases].

Authors:  J Ley-Zaporozhan; S Ley
Journal:  Radiologe       Date:  2014-12       Impact factor: 0.635

Review 2.  CT protocols in interstitial lung diseases--a survey among members of the European Society of Thoracic Imaging and a review of the literature.

Authors:  Helmut Prosch; Cornelia M Schaefer-Prokop; Edith Eisenhuber; Daniela Kienzl; Christian J Herold
Journal:  Eur Radiol       Date:  2012-12-13       Impact factor: 5.315

3.  CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society.

Authors:  David A Lynch; John H M Austin; James C Hogg; Philippe A Grenier; Hans-Ulrich Kauczor; Alexander A Bankier; R Graham Barr; Thomas V Colby; Jeffrey R Galvin; Pierre Alain Gevenois; Harvey O Coxson; Eric A Hoffman; John D Newell; Massimo Pistolesi; Edwin K Silverman; James D Crapo
Journal:  Radiology       Date:  2015-05-11       Impact factor: 11.105

4.  Efficiency and reproducibility in pulmonary nodule detection in simulated dose reduction lung CT images.

Authors:  Takeshi Kubo; Ayami Ohno Kishimoto; Kaori Togashi
Journal:  Eur J Radiol Open       Date:  2019-03-11
  4 in total

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