Literature DB >> 19045903

Development of a portable therapeutic and high intensity ultrasound system for military, medical, and research use.

George K Lewis1, William L Olbricht.   

Abstract

We have developed a portable high power ultrasound system with a very low output impedance amplifier circuit (less than 0.3 Omega) that can transfer more than 90% of the energy from a battery supply to the ultrasound transducer. The system can deliver therapeutic acoustical energy waves at lower voltages than those in conventional ultrasound systems because energy losses owing to a mismatched impedance are eliminated. The system can produce acoustic power outputs over the therapeutic range (greater then 50 W) from a PZT-4, 1.54 MHz, and 0.75 in diameter piezoelectric ceramic. It is lightweight, portable, and powered by a rechargeable battery. The portable therapeutic ultrasound unit has the potential to replace "plug-in" medical systems and rf amplifiers used in research. The system is capable of field service on its internal battery, making it especially useful for military, ambulatory, and remote medical applications.

Entities:  

Mesh:

Year:  2008        PMID: 19045903      PMCID: PMC2596633          DOI: 10.1063/1.3020704

Source DB:  PubMed          Journal:  Rev Sci Instrum        ISSN: 0034-6748            Impact factor:   1.523


  10 in total

1.  Real-time visualization of high-intensity focused ultrasound treatment using ultrasound imaging.

Authors:  S Vaezy; X Shi; R W Martin; E Chi; P I Nelson; M R Bailey; L A Crum
Journal:  Ultrasound Med Biol       Date:  2001-01       Impact factor: 2.998

Review 2.  Healing sound: the use of ultrasound in drug delivery and other therapeutic applications.

Authors:  Samir Mitragotri
Journal:  Nat Rev Drug Discov       Date:  2005-03       Impact factor: 84.694

3.  Current status of HIFU and cryotherapy in prostate cancer--a review.

Authors:  Gunnar Aus
Journal:  Eur Urol       Date:  2006-07-28       Impact factor: 20.096

Review 4.  Gene therapy progress and prospects: ultrasound for gene transfer.

Authors:  C M H Newman; T Bettinger
Journal:  Gene Ther       Date:  2007-03       Impact factor: 5.250

5.  Acoustic power calibration of high-intensity focused ultrasound transducers using a radiation force technique.

Authors:  Subha Maruvada; Gerald R Harris; Bruce A Herman; Randy L King
Journal:  J Acoust Soc Am       Date:  2007-03       Impact factor: 1.840

Review 6.  High intensity focused ultrasound: physical principles and devices.

Authors:  Gail Ter Haar; Constantin Coussios
Journal:  Int J Hyperthermia       Date:  2007-03       Impact factor: 3.914

7.  Cost-effective broad-band electrical impedance spectroscopy measurement circuit and signal analysis for piezo-materials and ultrasound transducers.

Authors:  George K Lewis; George K Lewis; William Olbricht
Journal:  Meas Sci Technol       Date:  2008-10       Impact factor: 2.046

8.  Arrays of multielement ultrasound applicators for interstitial hyperthermia.

Authors:  R J Lee; M Buchanan; L J Kleine; K Hynynen
Journal:  IEEE Trans Biomed Eng       Date:  1999-07       Impact factor: 4.538

9.  Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo.

Authors:  N I Vykhodtseva; K Hynynen; C Damianou
Journal:  Ultrasound Med Biol       Date:  1995       Impact factor: 2.998

10.  A NEW METHOD FOR THE GENERATION AND USE OF FOCUSED ULTRASOUND IN EXPERIMENTAL BIOLOGY.

Authors:  J G Lynn; R L Zwemer; A J Chick; A E Miller
Journal:  J Gen Physiol       Date:  1942-11-20       Impact factor: 4.086

  10 in total
  6 in total

1.  Time-reversal Techniques in Ultrasound-assisted Convection-enhanced Drug Delivery to the Brain: Technology Development and In Vivo Evaluation.

Authors:  George K Lewis; Sabrina Guarino; Gaurav Gandhi; Laurent Filinger; George K Lewis; Willam L Olbricht; Armen Sarvazyan
Journal:  Proc Meet Acoust       Date:  2011-07-10

2.  Wearable long duration ultrasound therapy pilot study in rotator cuff tendinopathy.

Authors:  George Lewis; Lyndon Hernandez; George K Lewis; Ralph Ortiz
Journal:  Proc Meet Acoust       Date:  2013-05-17

3.  Human Factors Engineering and testing for a wearable, long duration ultrasound system self-applied by an end user.

Authors:  Rebecca Taggart; Matthew D Langer; George K Lewis
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2014

4.  Sustained Acoustic Medicine: A Novel Long Duration Approach to Biomodulation Utilizing Low Intensity Therapeutic Ultrasound.

Authors:  Matthew D Langer; George K Lewis
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2015-05

5.  Design of low-loss 1-3 piezoelectric composites for high-power transducer applications.

Authors:  Hyeong Jae Lee; Shujun Zhang
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2012-09       Impact factor: 2.725

Review 6.  Driving circuitry for focused ultrasound noninvasive surgery and drug delivery applications.

Authors:  Munir M El-Desouki; Kullervo Hynynen
Journal:  Sensors (Basel)       Date:  2011-01-07       Impact factor: 3.576

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.