Literature DB >> 19043433

Out of the jaws of death: PRMT5 steers p53.

Shelley L Berger1.   

Abstract

The tumour suppressor p53 triggers either cell-cycle arrest or apoptosis. Now, arginine methylation joins a panoply of other post-translational modifications that regulate p53. PRMT5 mediates p53 methylation, which disposes the cell to arrest rather than death.

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Year:  2008        PMID： 19043433      PMCID： PMC3922054          DOI： 10.1038/ncb1208-1389

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  14 in total

1.  Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases.

Authors:  N A Barlev; L Liu; N H Chehab; K Mansfield; K G Harris; T D Halazonetis; S L Berger
Journal:  Mol Cell       Date:  2001-12       Impact factor: 17.970

Review 2.  Why is p53 acetylated?

Authors:  C Prives; J L Manley
Journal:  Cell       Date:  2001-12-28       Impact factor: 41.582

Review 3.  Multisite phosphorylation provides sophisticated regulation of transcription factors.

Authors:  Carina I Holmberg; Stefanie E F Tran; John E Eriksson; Lea Sistonen
Journal:  Trends Biochem Sci       Date:  2002-12       Impact factor: 13.807

4.  Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53.

Authors:  Woojin An; Jaehoon Kim; Robert G Roeder
Journal:  Cell       Date:  2004-06-11       Impact factor: 41.582

Review 5.  Transcriptional regulation by p53: one protein, many possibilities.

Authors:  O Laptenko; C Prives
Journal:  Cell Death Differ       Date:  2006-06       Impact factor: 15.828

Review 6.  State of the arg: protein methylation at arginine comes of age.

Authors:  A E McBride; P A Silver
Journal:  Cell       Date:  2001-07-13       Impact factor: 41.582

Review 7.  p53: a cellular Achilles' heel revealed.

Authors:  S K Burley
Journal:  Structure       Date:  1994-09-15       Impact factor: 5.006

8.  Regulation of transcription by a protein methyltransferase.

Authors:  D Chen; H Ma; H Hong; S S Koh; S M Huang; B T Schurter; D W Aswad; M R Stallcup
Journal:  Science       Date:  1999-06-25       Impact factor: 47.728

Review 9.  The p53 tumour suppressor gene.

Authors:  A J Levine; J Momand; C A Finlay
Journal:  Nature       Date:  1991-06-06       Impact factor: 49.962

10.  Arginine methylation regulates the p53 response.

Authors:  Martin Jansson; Stephen T Durant; Er-Chieh Cho; Sharon Sheahan; Mariola Edelmann; Benedikt Kessler; Nicholas B La Thangue
Journal:  Nat Cell Biol       Date:  2008-11-16       Impact factor: 28.824
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  10 in total

1.  Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway.

Authors:  Ricardo E Perez; Chad D Knights; Geetaram Sahu; Jason Catania; Vamsi K Kolukula; Daniel Stoler; Adolf Graessmann; Vasily Ogryzko; Michael Pishvaian; Christopher Albanese; Maria Laura Avantaggiati
Journal:  J Cell Physiol       Date:  2010-11       Impact factor: 6.384

Review 2.  New drugs for new targets in lymphoma.

Authors:  Anas Younes
Journal:  Hematol Oncol       Date:  2019-06       Impact factor: 5.271

3.  Lysine methylation of promoter-bound transcription factors and relevance to cancer.

Authors:  George R Stark; Yuxin Wang; Tao Lu
Journal:  Cell Res       Date:  2010-12-14       Impact factor: 25.617

4.  Protein arginine methyltransferase 5 regulates multiple signaling pathways to promote lung cancer cell proliferation.

Authors:  Xiumei Sheng; Zhengxin Wang
Journal:  BMC Cancer       Date:  2016-08-02       Impact factor: 4.430

5.  The Cellular p53 Inhibitor MDM2 and the Growth Factor Receptor FLT3 as Biomarkers for Treatment Responses to the MDM2-Inhibitor Idasanutlin and the MEK1 Inhibitor Cobimetinib in Acute Myeloid Leukemia.

Authors:  Katja Seipel; Miguel A T Marques; Corinne Sidler; Beatrice U Mueller; Thomas Pabst
Journal:  Cancers (Basel)       Date:  2018-05-31       Impact factor: 6.639

Review 6.  The Role of JMY in p53 Regulation.

Authors:  Omanma Adighibe; Francesco Pezzella
Journal:  Cancers (Basel)       Date:  2018-05-31       Impact factor: 6.639

7.  PRMT5-TRIM21 interaction regulates the senescence of osteosarcoma cells by targeting the TXNIP/p21 axis.

Authors:  Yu-Hang Li; Kui-Leung Tong; Jun-Lei Lu; Jie-Bin Lin; Zhen-Yan Li; Yuan Sang; Abdelmoumin Ghodbane; Xue-Juan Gao; Man-Seng Tam; Chang-Deng Hu; Huan-Tian Zhang; Zhen-Gang Zha
Journal:  Aging (Albany NY)       Date:  2020-02-05       Impact factor: 5.682

8.  Targeting methyltransferase PRMT5 retards the carcinogenesis and metastasis of HNSCC via epigenetically inhibiting Twist1 transcription.

Authors:  Zhaona Fan; Lihong He; Mianxiang Li; Ruoyan Cao; Miao Deng; Fan Ping; Xueyi Liang; Yuan He; Tong Wu; Xiaoan Tao; Jian Xu; Bin Cheng; Juan Xia
Journal:  Neoplasia       Date:  2020-10-10       Impact factor: 5.715

Review 9.  Preventing Neurodegeneration by Controlling Oxidative Stress: The Role of OXR1.

Authors:  Michael R Volkert; David J Crowley
Journal:  Front Neurosci       Date:  2020-12-15       Impact factor: 4.677

Review 10.  Regulating tumor suppressor genes: post-translational modifications.

Authors:  Ling Chen; Shuang Liu; Yongguang Tao
Journal:  Signal Transduct Target Ther       Date:  2020-06-10
  10 in total

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