Literature DB >> 19037639

Constant ambient temperature of 24 degrees C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter.

Katherine A Zukotynski1, Frederic H Fahey, Stephen Laffin, Royal Davis, S Ted Treves, Frederick D Grant, Laura A Drubach.   

Abstract

PURPOSE: The aim of this study was to determine if warming patients prior to and during (18)F-FDG uptake by controlling the room temperature could decrease uptake by brown adipose tissue (BAT).
METHODS: A group of 40 children underwent (18)F-FDG PET after being kept in the injection room at a constant temperature of 24 degrees C for half an hour before and 1 hour after intravenous tracer administration. The rate of uptake by BAT in this group was compared to the uptake in a control group of 45 patients who underwent PET when the injection room temperature was 21 degrees C.
RESULTS: Uptake by BAT occurred in 5% of studies in the temperature-controlled room compared to 31% of studies performed when the injection room temperature was 21 degrees C (p<0.002).
CONCLUSION: Maintaining room temperature at a constant 24 degrees C, half an hour prior to and during the period of FDG uptake significantly decreases accumulation of FDG in BAT in children.

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Year:  2008        PMID: 19037639     DOI: 10.1007/s00259-008-0983-y

Source DB:  PubMed          Journal:  Eur J Nucl Med Mol Imaging        ISSN: 1619-7070            Impact factor:   9.236


  16 in total

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  20 in total

1.  Seasonal variation in the effect of constant ambient temperature of 24 degrees C in reducing FDG uptake by brown adipose tissue in children.

Authors:  Katherine A Zukotynski; Frederic H Fahey; Stephen Laffin; Royal Davis; S Ted Treves; Frederick D Grant; Laura A Drubach
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