| Literature DB >> 26167397 |
Chioma Izzi-Engbeaya1, Victoria Salem1, Rajveer S Atkar1, Waljit S Dhillo1.
Abstract
There has been resurgence in interest in brown adipose tissue (BAT) following radiological and histological identification of metabolically active BAT in adult humans. Imaging enables BAT to be studied non-invasively and therefore imaging studies have contributed a significant amount to what is known about BAT function in humans. In this review the current knowledge (derived from imaging studies) about the prevalence, function, activity and regulation of BAT in humans (as well as relevant rodent studies), will be summarized.Entities:
Keywords: 11C-MHED, [11C]-meta-hydroxyephedrine; 18F-FDG, [18F]-fluorodeoxyglucose; 99mTc-sestamibi, technetium-99m sestamibi; 99mTc-tetrofosmin, technetium-99m tetrofosmin; ATP, adenosine triphosphate; BAT, brown adipose tissue; BMI, body mass index; BOLD, blood oxygen level dependent; CIT, cold-induced thermogenesis; IQR, interquartile range; MRI, magnetic resonance imaging; NST, non-shivering thermogenesis; PET-CT, positron emission tomography-computed tomography; SPECT, single photon emission CT; UCP-1, uncoupling protein 1; WAT, white adipose tissue; brown adipose tissue; energy expenditure; imaging; metabolism; thermogenesis
Year: 2014 PMID： 26167397 PMCID： PMC4497292 DOI： 10.4161/21623945.2014.965609
Source DB: PubMed Journal: Adipocyte ISSN： 2162-3945 Impact factor: 4.534