Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Reverse genetics in zebrafish by TILLING.

Literature DB >> 19028802

Reverse genetics in zebrafish by TILLING.

Cecilia B Moens¹, Thomas M Donn, Emma R Wolf-Saxon, Taylur P Ma.

Abstract

TILLING, for Targeting Induced Local Lesions in Genomes, is a reverse genetics strategy that identifies mutations in specific genes of interest in chemically mutagenized populations. First described in 2000 for mutation detection in Arabidopsis, TILLING is now used in a wide range of plants including soybean, rice, barley and maize as well as for animal model systems, including Arabidopsis, Drosophila, Caenorhabditis elegans, rat, medaka and zebrafish and for the discovery of naturally occurring polymorphisms in humans. This review summarizes current TILLING methodologies as they have been applied to the zebrafish, ongoing TILLING projects and resources in the zebrafish community, and the future of zebrafish TILLING.

Entities: Species

Mesh：

Substances：
Mutagens
Ethylnitrosourea

Year: 2008 PMID： 19028802 PMCID： PMC2899843 DOI： 10.1093/bfgp/eln046

Source DB: PubMed Journal: Brief Funct Genomic Proteomic ISSN： 1473-9550

35 in total

1. High-throughput screening for induced point mutations.

Authors: T Colbert; B J Till; R Tompa; S Reynolds; M N Steine; A T Yeung; C M McCallum; L Comai; S Henikoff
Journal: Plant Physiol Date: 2001-06 Impact factor: 8.340

2. Target-selected inactivation of the zebrafish rag1 gene.

Authors: Erno Wienholds; Stefan Schulte-Merker; Brigitte Walderich; Ronald H A Plasterk
Journal: Science Date: 2002-07-05 Impact factor: 47.728

3. Web-based primer design for single nucleotide polymorphism analysis.

Authors: Michael M Neff; Edward Turk; Michael Kalishman
Journal: Trends Genet Date: 2002-12 Impact factor: 11.639

4. Efficient target-selected mutagenesis in zebrafish.

Authors: Erno Wienholds; Freek van Eeden; Marit Kosters; Josine Mudde; Ronald H A Plasterk; Edwin Cuppen
Journal: Genome Res Date: 2003-11-12 Impact factor: 9.043

5. Identification of selected gamma-ray induced deficiencies in zebrafish using multiplex polymerase chain reaction.

Authors: A Fritz; M Rozowski; C Walker; M Westerfield
Journal: Genetics Date: 1996-12 Impact factor: 4.562

6. Targeted screening for induced mutations.

Authors: C M McCallum; L Comai; E A Greene; S Henikoff
Journal: Nat Biotechnol Date: 2000-04 Impact factor: 54.908

7. The Wnt/beta-catenin pathway regulates cardiac valve formation.

Authors: Adam F L Hurlstone; Anna-Pavlina G Haramis; Erno Wienholds; Harry Begthel; Jeroen Korving; Fredericus Van Eeden; Edwin Cuppen; Danica Zivkovic; Ronald H A Plasterk; Hans Clevers
Journal: Nature Date: 2003-10-09 Impact factor: 49.962

8. The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

Authors: Erno Wienholds; Marco J Koudijs; Freek J M van Eeden; Edwin Cuppen; Ronald H A Plasterk
Journal: Nat Genet Date: 2003-10-05 Impact factor: 38.330

9. Generation of medaka gene knockout models by target-selected mutagenesis.

Authors: Yoshihito Taniguchi; Shunichi Takeda; Makoto Furutani-Seiki; Yasuhiro Kamei; Takeshi Todo; Takao Sasado; Tomonori Deguchi; Hisato Kondoh; Josine Mudde; Mitsuyoshi Yamazoe; Masayuki Hidaka; Hiroshi Mitani; Atsushi Toyoda; Yoshiyuki Sakaki; Ronald H A Plasterk; Edwin Cuppen
Journal: Genome Biol Date: 2006 Impact factor: 13.583

10. Discovery of induced point mutations in maize genes by TILLING.

Authors: Bradley J Till; Steven H Reynolds; Clifford Weil; Nathan Springer; Chris Burtner; Kim Young; Elisabeth Bowers; Christine A Codomo; Linda C Enns; Anthony R Odden; Elizabeth A Greene; Luca Comai; Steven Henikoff
Journal: BMC Plant Biol Date: 2004-07-28 Impact factor: 4.215

82 in total

Review 5. Hepatocyte polarity.

Authors: Aleksandr Treyer; Anne Müsch
Journal: Compr Physiol Date: 2013-01 Impact factor: 9.090

Reverse genetics in zebrafish by TILLING.

1. High-throughput screening for induced point mutations.

2. Target-selected inactivation of the zebrafish rag1 gene.

3. Web-based primer design for single nucleotide polymorphism analysis.

4. Efficient target-selected mutagenesis in zebrafish.

5. Identification of selected gamma-ray induced deficiencies in zebrafish using multiplex polymerase chain reaction.

6. Targeted screening for induced mutations.

7. The Wnt/beta-catenin pathway regulates cardiac valve formation.

8. The microRNA-producing enzyme Dicer1 is essential for zebrafish development.

9. Generation of medaka gene knockout models by target-selected mutagenesis.

10. Discovery of induced point mutations in maize genes by TILLING.

Review 1. Modeling human neurodegenerative diseases in transgenic systems.

2. Efficient shRNA-mediated inhibition of gene expression in zebrafish.

3. Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples.

4. A novel role for MuSK and non-canonical Wnt signaling during segmental neural crest cell migration.

Review 5. Hepatocyte polarity.

Review 6. Zebrafish models of human liver development and disease.

Review 7. Expanding horizons: ciliary proteins reach beyond cilia.

8. All-in-one live: genes trapped, tagged and conditionally broken.

Review 9. Epigenetics, development, and cancer: zebrafish make their mark..

10. Maternal pak4 expression is required for primitive myelopoiesis in zebrafish.