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Literature DB >> 18991466

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2007.

Roland E Dolle¹, Bertrand Le Bourdonnec, Allan J Goodman, Guillermo A Morales, Craig J Thomas, Wei Zhang.

Abstract

Mesh：

Substances：
Small Molecule Libraries

Year: 2008 PMID： 18991466 DOI： 10.1021/cc800119z

Source DB: PubMed Journal: J Comb Chem ISSN： 1520-4766

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19 in total

1. Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy.

Authors: Qin Zang; Salim Javed; Patrick Porubsky; Farman Ullah; Benjamin Neuenswander; Gerald H Lushington; Fatima Z Basha; Michael G Organ; Paul R Hanson
Journal: ACS Comb Sci Date: 2012-02-06 Impact factor: 3.784

2. Facile (triazolyl)methylation of MACOS-derived benzofused sultams utilizing ROMP-derived OTP reagents.

Authors: Saqib Faisal; Farman Ullah; Pradip K Maity; Alan Rolfe; Thiwanka B Samarakoon; Patrick Porubsky; Benjamin Neuenswander; Gerald H Lushington; Fatima Z Basha; Michael G Organ; Paul R Hanson
Journal: ACS Comb Sci Date: 2012-03-05 Impact factor: 3.784

3. Recent progress on fluorous synthesis of biologically interesting compounds.

Authors: Zhong-Xing Jiang; Sanjun Zhi; Wei Zhang
Journal: Mol Divers Date: 2014-01-20 Impact factor: 2.943

Review 4. Malononitrile dimer as a privileged reactant in design and skeletal diverse synthesis of heterocyclic motifs.

Authors: Ahmad Shaabani; Seyyed Emad Hooshmand
Journal: Mol Divers Date: 2018-01-03 Impact factor: 2.943

5. Triazole-containing isothiazolidine 1,1-dioxide library synthesis: one-pot, multi-component protocols for small molecular probe discovery.

Authors: Alan Rolfe; Thomas O Painter; Naeem Asad; Moon Young Hur; Kyu Ok Jeon; Marek Brzozowski; Sarra V Klimberg; Patrick Porubsky; Benjamin Neuenswander; Gerald H Lushington; Conrad Santini; Paul R Hanson
Journal: ACS Comb Sci Date: 2011-08-25 Impact factor: 3.784

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2007.

1. Synthesis of a unique isoindoline/tetrahydroisoquinoline-based tricyclic sultam library utilizing a Heck-aza-Michael strategy.

2. Facile (triazolyl)methylation of MACOS-derived benzofused sultams utilizing ROMP-derived OTP reagents.

3. Recent progress on fluorous synthesis of biologically interesting compounds.

Review 4. Malononitrile dimer as a privileged reactant in design and skeletal diverse synthesis of heterocyclic motifs.

5. Triazole-containing isothiazolidine 1,1-dioxide library synthesis: one-pot, multi-component protocols for small molecular probe discovery.

6. Copper-catalyzed electrophilic amination of organolithiums mediated by recoverable siloxane transfer agents.

7. Synthesis of novel 4H-pyrimido[1,6-a]pyrimidines via a one-pot three-component condensation.

8. Synthesis of amino-benzothiaoxazepine-1,1-dioxides utilizing a microwave-assisted, S(N)Ar protocol.

9. Reagent based DOS: a "Click, Click, Cyclize" strategy to probe chemical space.

10. Efficient alkene synthesis on solid support using the Julia-Kocienski coupling.