Literature DB >> 18984154

Knockdown screens to knockout HIV-1.

Stephen P Goff1.   

Abstract

Three recent screens use siRNAs to identify host genes that are critical for HIV-1 replication. These screens have uncovered hundreds of human genes not previously known to be commandeered by the virus during infection. Although some caveats remain, this screening approach opens up a new landscape of viral-host interactions for future exploration.

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Year:  2008        PMID： 18984154      PMCID： PMC3598618          DOI： 10.1016/j.cell.2008.10.007

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  13 in total

1.  Retroviruses and yeast retrotransposons use overlapping sets of host genes.

Authors:  Becky Irwin; Michael Aye; Pierre Baldi; Nadejda Beliakova-Bethell; Henry Cheng; Yimeng Dou; Willy Liou; Suzanne Sandmeyer
Journal:  Genome Res       Date:  2005-04-18       Impact factor: 9.043

2.  Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance.

Authors:  D T Scholes; M Banerjee; B Bowen; M J Curcio
Journal:  Genetics       Date:  2001-12       Impact factor: 4.562

3.  Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae.

Authors:  Michael Aye; Becky Irwin; Nadejda Beliakova-Bethell; Eric Chen; Jennifer Garrus; Suzanne Sandmeyer
Journal:  Genetics       Date:  2004-11       Impact factor: 4.562

4.  Functional genomics reveals relationships between the retrovirus-like Ty1 element and its host Saccharomyces cerevisiae.

Authors:  Jacqulyn L Griffith; Laura E Coleman; Adam S Raymond; Summer G Goodson; William S Pittard; Circe Tsui; Scott E Devine
Journal:  Genetics       Date:  2003-07       Impact factor: 4.562

5.  Genome-scale RNAi screen for host factors required for HIV replication.

Authors:  Honglin Zhou; Min Xu; Qian Huang; Adam T Gates; Xiaohua D Zhang; John C Castle; Erica Stec; Marc Ferrer; Berta Strulovici; Daria J Hazuda; Amy S Espeseth
Journal:  Cell Host Microbe       Date:  2008-10-30       Impact factor: 21.023

6.  LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes.

Authors:  Manuel Llano; Maria Vanegas; Oliver Fregoso; Dyana Saenz; Susan Chung; Mary Peretz; Eric M Poeschla
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

7.  Transportin-SR2 imports HIV into the nucleus.

Authors:  Frauke Christ; Wannes Thys; Jan De Rijck; Rik Gijsbers; Alberto Albanese; Daniele Arosio; Stephane Emiliani; Jean-Christophe Rain; Richard Benarous; Anna Cereseto; Zeger Debyser
Journal:  Curr Biol       Date:  2008-08-26       Impact factor: 10.834

8.  LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells.

Authors:  Goedele Maertens; Peter Cherepanov; Wim Pluymers; Katrien Busschots; Erik De Clercq; Zeger Debyser; Yves Engelborghs
Journal:  J Biol Chem       Date:  2003-06-09       Impact factor: 5.157

9.  Identification of host proteins required for HIV infection through a functional genomic screen.

Authors:  Abraham L Brass; Derek M Dykxhoorn; Yair Benita; Nan Yan; Alan Engelman; Ramnik J Xavier; Judy Lieberman; Stephen J Elledge
Journal:  Science       Date:  2008-01-10       Impact factor: 47.728

10.  Drosophila RNAi screen identifies host genes important for influenza virus replication.

Authors:  Linhui Hao; Akira Sakurai; Tokiko Watanabe; Ericka Sorensen; Chairul A Nidom; Michael A Newton; Paul Ahlquist; Yoshihiro Kawaoka
Journal:  Nature       Date:  2008-07-09       Impact factor: 49.962
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  61 in total

Review 1.  Current progress in the development of RNAi-based therapeutics for HIV-1.

Authors:  J Zhou; J J Rossi
Journal:  Gene Ther       Date:  2011-09-29       Impact factor: 5.250

2.  HIV-1 Nef-associated Factor 1 Enhances Viral Production by Interacting with CRM1 to Promote Nuclear Export of Unspliced HIV-1 gag mRNA.

Authors:  Xiao-Xin Ren; Hai-Bo Wang; Chuan Li; Jin-Feng Jiang; Si-Dong Xiong; Xia Jin; Li Wu; Jian-Hua Wang
Journal:  J Biol Chem       Date:  2016-01-05       Impact factor: 5.157

3.  A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

Authors:  Man Lung Yeung; Laurent Houzet; Venkat S R K Yedavalli; Kuan-Teh Jeang
Journal:  J Biol Chem       Date:  2009-05-20       Impact factor: 5.157

4.  Delineation of key regulatory elements identifies points of vulnerability in the mitogen-activated signaling network.

Authors:  Noor Jailkhani; Srikanth Ravichandran; Shubhada R Hegde; Zaved Siddiqui; Shekhar C Mande; Kanury V S Rao
Journal:  Genome Res       Date:  2011-08-24       Impact factor: 9.043

5.  Mining the human complexome database identifies RBM14 as an XPO1-associated protein involved in HIV-1 Rev function.

Authors:  Sona Budhiraja; Hongbing Liu; Jacob Couturier; Anna Malovannaya; Jun Qin; Dorothy E Lewis; Andrew P Rice
Journal:  J Virol       Date:  2015-01-14       Impact factor: 5.103

Review 6.  The roles of tetraspanins in HIV-1 replication.

Authors:  Markus Thali
Journal:  Curr Top Microbiol Immunol       Date:  2009       Impact factor: 4.291

Review 7.  Hunting Viral Receptors Using Haploid Cells.

Authors:  Sirika Pillay; Jan E Carette
Journal:  Annu Rev Virol       Date:  2015-07-02       Impact factor: 10.431

8.  Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cells.

Authors:  Sylvie Rato; Sara Maia; Paula M Brito; Leonor Resende; Carina F Pereira; Catarina Moita; Rui P Freitas; José Moniz-Pereira; Nir Hacohen; Luis Ferreira Moita; Joao Goncalves
Journal:  PLoS One       Date:  2010-02-17       Impact factor: 3.240

9.  A simple fluorescence based assay for quantification of human immunodeficiency virus particle release.

Authors:  Johannes Hermle; Maria Anders; Anke-Mareil Heuser; Barbara Müller
Journal:  BMC Biotechnol       Date:  2010-04-20       Impact factor: 2.563

10.  siRNA and shRNA screens advance key understanding of host factors required for HIV-1 replication.

Authors:  Kin-Hang Kok; Ting Lei; Dong-Yan Jin
Journal:  Retrovirology       Date:  2009-08-27       Impact factor: 4.602
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