Literature DB >> 18983146

A unifying nitrososynthase involved in nitrosugar biosynthesis.

Yunfeng Hu1, Ahmad Al-Mestarihi, Catherine L Grimes, Daniel Kahne, Brian O Bachmann.   

Abstract

Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively.

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Year:  2008        PMID： 18983146      PMCID： PMC2661260          DOI： 10.1021/ja8051415

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  21 in total

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Authors:  H Chen; M G Thomas; B K Hubbard; H C Losey; C T Walsh; M D Burkart
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

2.  NAD(P)H-flavin oxidoreductase from the bioluminescent bacterium, Vibrio fischeri ATCC 7744, is a flavoprotein.

Authors:  S Inouye
Journal:  FEBS Lett       Date:  1994-06-27       Impact factor: 4.124

3.  A practical method for the stereoselective generation of beta-2-deoxy glycosyl phosphates.

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4.  Gene overexpression, purification, and identification of a desulfurization enzyme from Rhodococcus sp. strain IGTS8 as a sulfide/sulfoxide monooxygenase.

Authors:  B Lei; S C Tu
Journal:  J Bacteriol       Date:  1996-10       Impact factor: 3.490

Review 5.  Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria.

Authors:  Shannon C Timmons; Jon S Thorson
Journal:  Curr Opin Chem Biol       Date:  2008-04-18       Impact factor: 8.822

6.  Liquid chromatographic analysis of nucleosides and their mono-, di- and triphosphates using porous graphitic carbon stationary phase coupled with electrospray mass spectrometry.

Authors:  Jinsong Xing; Atsu Apedo; Adrienne Tymiak; Ning Zhao
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7.  Protorubradirin, an antibiotic containing a C-nitroso-sugar fragment, is the true secondary metabolite produced by Streptomyces achromogenes var. rubradiris. Rubradirin, described earlier, is its photo-oxidation product.

Authors:  B Bannister; B A Zapotocky
Journal:  J Antibiot (Tokyo)       Date:  1992-08       Impact factor: 2.649

8.  Kijanimicin (Sch 25663), a novel antibiotic produced by Actinomadura kijaniata SCC 1256. Fermentation, isolation, characterization and biological properties.

Authors:  J A Waitz; A C Horan; M Kalyanpur; B K Lee; D Loebenberg; J A Marquez; G Miller; M G Patel
Journal:  J Antibiot (Tokyo)       Date:  1981-09       Impact factor: 2.649

9.  The NAD(P)H:flavin oxidoreductase from Escherichia coli as a source of superoxide radicals.

Authors:  P Gaudu; D Touati; V Nivière; M Fontecave
Journal:  J Biol Chem       Date:  1994-03-18       Impact factor: 5.157

10.  Evernitrose, a naturally occurring nitro sugar from everninomicins.

Authors:  A K Ganguly; O Z Sarre; H Reimann
Journal:  J Am Chem Soc       Date:  1968-12-04       Impact factor: 15.419
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  13 in total

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Authors:  Shanteri Singh; George N Phillips; Jon S Thorson
Journal:  Nat Prod Rep       Date:  2012-06-12       Impact factor: 13.423

2.  Metalloenzymes: Natural product nitrosation.

Authors:  Roland D Kersten; Pieter C Dorrestein
Journal:  Nat Chem Biol       Date:  2010-09       Impact factor: 15.040

3.  Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis .

Authors:  Jessica L Vey; Ahmad Al-Mestarihi; Yunfeng Hu; Michael A Funk; Brian O Bachmann; T M Iverson
Journal:  Biochemistry       Date:  2010-11-02       Impact factor: 3.162

4.  Nitrososynthase-triggered oxidative carbon-carbon bond cleavage in baumycin biosynthesis.

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Review 5.  Mechanisms and structures of vitamin B(6)-dependent enzymes involved in deoxy sugar biosynthesis.

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Review 6.  Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.

Authors:  Abraham J Waldman; Tai L Ng; Peng Wang; Emily P Balskus
Journal:  Chem Rev       Date:  2017-04-04       Impact factor: 60.622

7.  Stabilization of C4a-hydroperoxyflavin in a two-component flavin-dependent monooxygenase is achieved through interactions at flavin N5 and C4a atoms.

Authors:  Kittisak Thotsaporn; Pirom Chenprakhon; Jeerus Sucharitakul; Andrea Mattevi; Pimchai Chaiyen
Journal:  J Biol Chem       Date:  2011-06-16       Impact factor: 5.157

8.  Analysis of the Pseudouridimycin Biosynthetic Pathway Provides Insights into the Formation of C-nucleoside Antibiotics.

Authors:  Margherita Sosio; Eleonora Gaspari; Marianna Iorio; Silvia Pessina; Marnix H Medema; Alice Bernasconi; Matteo Simone; Sonia I Maffioli; Richard H Ebright; Stefano Donadio
Journal:  Cell Chem Biol       Date:  2018-03-15       Impact factor: 8.116

Review 9.  The biosynthesis of nitrogen-, sulfur-, and high-carbon chain-containing sugars.

Authors:  Chia-I Lin; Reid M McCarty; Hung-wen Liu
Journal:  Chem Soc Rev       Date:  2013-01-25       Impact factor: 54.564

10.  Structure of DnmZ, a nitrososynthase in the Streptomyces peucetius anthracycline biosynthetic pathway.

Authors:  Lauren Sartor; Charmaine Ibarra; Ahmad Al-Mestarihi; Brian O Bachmann; Jessica L Vey
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-09-23       Impact factor: 1.056
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