Literature DB >> 1896023

A quantitative assay to measure chromosome stability in Schizosaccharomyces pombe.

Z Bodi1, A Gysler-Junker, J Kohli.   

Abstract

The fidelity of mitotic chromosome transmission in Schizosaccharomyces pombe was estimated quantitatively by using cycloheximide resistance as a means to select cells that had undergone chromosome loss or nondisjunction. We aimed to investigate the connection between recombination and mitotic chromosome stability. A number of mutants defective in mitotic recombination such as cdc17-L16, rec59-72, and rec50-25 were tested and in these an approximately ten fold elevation of mitotic haploidization rate was found compared with controls. Our data suggest that recombination is important in controlling the maintenance of chromosomes during mitosis.

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Year:  1991        PMID： 1896023     DOI： 10.1007/bf00264215

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  15 in total

1.  The detection of mitotic and meiotic aneuploidy in yeast using a gene dosage selection system.

Authors:  S G Whittaker; B M Rockmill; A E Blechl; D H Maloney; M A Resnick; S Fogel
Journal:  Mol Gen Genet       Date:  1988-12

2.  The distribution of the numbers of mutants in bacterial populations.

Authors:  D E LEA; C A COULSON
Journal:  J Genet       Date:  1949-12       Impact factor: 1.166

3.  Meiotic disjunction of homologs in Saccharomyces cerevisiae is directed by pairing and recombination of the chromosome arms but not by pairing of the centromeres.

Authors:  R T Surosky; B K Tye
Journal:  Genetics       Date:  1988-06       Impact factor: 4.562

4.  Genes involved in mating type expression of fission yeast.

Authors:  R Egel
Journal:  Mol Gen Genet       Date:  1973-05-28

5.  Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss.

Authors:  P Hieter; C Mann; M Snyder; R W Davis
Journal:  Cell       Date:  1985-02       Impact factor: 41.582

6.  DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe.

Authors:  T Uemura; H Ohkura; Y Adachi; K Morino; K Shiozaki; M Yanagida
Journal:  Cell       Date:  1987-09-11       Impact factor: 41.582

7.  The NDA3 gene of fission yeast encodes beta-tubulin: a cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis.

Authors:  Y Hiraoka; T Toda; M Yanagida
Journal:  Cell       Date:  1984-12       Impact factor: 41.582

Review 8.  Chromosome error propagation and cancer.

Authors:  R Holliday
Journal:  Trends Genet       Date:  1989-02       Impact factor: 11.639

9.  Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis.

Authors:  H Ohkura; Y Adachi; N Kinoshita; O Niwa; T Toda; M Yanagida
Journal:  EMBO J       Date:  1988-05       Impact factor: 11.598

10.  Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosaccharomyces pombe: video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a DNA-binding fluorescent probe.

Authors:  T Toda; M Yamamoto; M Yanagida
Journal:  J Cell Sci       Date:  1981-12       Impact factor: 5.285
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  6 in total

1.  Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.

Authors:  H A Snaith; G W Brown; S L Forsburg
Journal:  Mol Cell Biol       Date:  2000-11       Impact factor: 4.272

2.  Mitotic chromosome biorientation in fission yeast is enhanced by dynein and a minus-end-directed, kinesin-like protein.

Authors:  Ekaterina L Grishchuk; Ilia S Spiridonov; J Richard McIntosh
Journal:  Mol Biol Cell       Date:  2007-04-04       Impact factor: 4.138

Review 3.  Genetic instability in budding and fission yeast-sources and mechanisms.

Authors:  Adrianna Skoneczna; Aneta Kaniak; Marek Skoneczny
Journal:  FEMS Microbiol Rev       Date:  2015-06-24       Impact factor: 16.408

4.  A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase.

Authors:  Amy D Fung; Jiongwen Ou; Stephanie Bueler; Grant W Brown
Journal:  Mol Cell Biol       Date:  2002-07       Impact factor: 4.272

Review 5.  Homologous recombination in fission yeast: absence of crossover interference and synaptonemal complex.

Authors:  J Kohli; J Bähler
Journal:  Experientia       Date:  1994-03-15

6.  Homology-directed repair involves multiple strand invasion cycles in fission yeast.

Authors:  Amanda J Vines; Kenneth Cox; Bryan A Leland; Megan C King
Journal:  Mol Biol Cell       Date:  2022-01-26       Impact factor: 3.612
  6 in total

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