Literature DB >> 18958459

Impact of CYP2C19 polymorphisms on the clinical action of proton pump inhibitors (PPIs).

Ulrich Klotz.   

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Year:  2008        PMID: 18958459     DOI: 10.1007/s00228-008-0571-x

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


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  14 in total

1.  Different dosage regimens of rabeprazole for nocturnal gastric acid inhibition in relation to cytochrome P450 2C19 genotype status.

Authors:  Mitsushige Sugimoto; Takahisa Furuta; Naohito Shirai; Masayoshi Kajimura; Akira Hishida; Masaharu Sakurai; Kyoichi Ohashi; Takashi Ishizaki
Journal:  Clin Pharmacol Ther       Date:  2004-10       Impact factor: 6.875

2.  Omeprazole: a possible new candidate influencing the antiplatelet effect of clopidogrel.

Authors:  Paul A Gurbel; Wei C Lau; Udaya S Tantry
Journal:  J Am Coll Cardiol       Date:  2008-01-22       Impact factor: 24.094

Review 3.  Proton pump inhibitors: an update of their clinical use and pharmacokinetics.

Authors:  Shaojun Shi; Ulrich Klotz
Journal:  Eur J Clin Pharmacol       Date:  2008-08-05       Impact factor: 2.953

4.  A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants.

Authors:  Sarah C Sim; Carl Risinger; Marja-Liisa Dahl; Eleni Aklillu; Magnus Christensen; Leif Bertilsson; Magnus Ingelman-Sundberg
Journal:  Clin Pharmacol Ther       Date:  2006-01       Impact factor: 6.875

5.  Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects.

Authors:  Jean-Sébastien Hulot; Alessandra Bura; Eric Villard; Michel Azizi; Véronique Remones; Catherine Goyenvalle; Martine Aiach; Philippe Lechat; Pascale Gaussem
Journal:  Blood       Date:  2006-06-13       Impact factor: 22.113

6.  Esomeprazole-induced healing of gastroesophageal reflux disease is unrelated to the genotype of CYP2C19: evidence from clinical and pharmacokinetic data.

Authors:  Matthias Schwab; Ulrich Klotz; Ute Hofmann; Elke Schaeffeler; Andreas Leodolter; Peter Malfertheiner; Gerhard Treiber
Journal:  Clin Pharmacol Ther       Date:  2005-12       Impact factor: 6.875

Review 7.  Clinical impact of CYP2C19 polymorphism on the action of proton pump inhibitors: a review of a special problem.

Authors:  U Klotz
Journal:  Int J Clin Pharmacol Ther       Date:  2006-07       Impact factor: 1.366

Review 8.  Review article: relationship between the metabolism and efficacy of proton pump inhibitors--focus on rabeprazole.

Authors:  J Horn
Journal:  Aliment Pharmacol Ther       Date:  2004-11       Impact factor: 8.171

9.  Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) study.

Authors:  Martine Gilard; Bertrand Arnaud; Jean-Christophe Cornily; Grégoire Le Gal; Karine Lacut; Geneviève Le Calvez; Jacques Mansourati; Dominique Mottier; Jean-François Abgrall; Jacques Boschat
Journal:  J Am Coll Cardiol       Date:  2008-01-22       Impact factor: 24.094

10.  Cytochrome P450 2C19 681G>A polymorphism and high on-clopidogrel platelet reactivity associated with adverse 1-year clinical outcome of elective percutaneous coronary intervention with drug-eluting or bare-metal stents.

Authors:  Dietmar Trenk; Willibald Hochholzer; Martin F Fromm; Ligia-Emilia Chialda; Andreas Pahl; Christian M Valina; Christian Stratz; Peter Schmiebusch; Hans-Peter Bestehorn; Heinz Joachim Büttner; Franz-Josef Neumann
Journal:  J Am Coll Cardiol       Date:  2008-05-20       Impact factor: 24.094

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  4 in total

Review 1.  Refractory chronic cough due to gastroesophageal reflux: Definition, mechanism and management.

Authors:  Han-Jing Lv; Zhong-Min Qiu
Journal:  World J Methodol       Date:  2015-09-26

2.  A stepwise protocol for the treatment of refractory gastroesophageal reflux-induced chronic cough.

Authors:  Xianghuai Xu; Hanjing Lv; Li Yu; Qiang Chen; Siwei Liang; Zhongmin Qiu
Journal:  J Thorac Dis       Date:  2016-01       Impact factor: 2.895

3.  PK/PD modeling of rabeprazole in CYP2C19 genotypes: consideration of the influence of thio-ether metabolite, CYP3A4, accumulation and CYP2D6 polymorphism may help to better develop and validate the model.

Authors:  Nuggehally R Srinivas
Journal:  Eur J Clin Pharmacol       Date:  2011-03-19       Impact factor: 2.953

4.  Pharmacokinetics and Pharmacodynamics of Esomeprazole/Sodium Bicarbonate Immediate-Release Capsules in Healthy Chinese Volunteers: A Cross-Over, Randomized Controlled Trial.

Authors:  Shan Jing; Yue Zhu; Wenfang Liu; Kexu Yang; Lili Hu; Dan Deng; Chunyan Lu; Yang Lin
Journal:  Adv Ther       Date:  2021-02-11       Impact factor: 3.845

  4 in total

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