Literature DB >> 21424385

PK/PD modeling of rabeprazole in CYP2C19 genotypes: consideration of the influence of thio-ether metabolite, CYP3A4, accumulation and CYP2D6 polymorphism may help to better develop and validate the model.

Nuggehally R Srinivas1.   

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Year:  2011        PMID: 21424385     DOI: 10.1007/s00228-011-1027-2

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


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  6 in total

1.  Effect of CYP2C19 genotypes on the pharmacokinetic/pharmacodynamic relationship of rabeprazole after a single oral dose in healthy Chinese volunteers.

Authors:  Yu-Cheng Sheng; Kun Wang; Ying-Chun He; Juan Yang; Qing-Shan Zheng
Journal:  Eur J Clin Pharmacol       Date:  2010-09-14       Impact factor: 2.953

2.  Impact of CYP2C19 polymorphisms on the clinical action of proton pump inhibitors (PPIs).

Authors:  Ulrich Klotz
Journal:  Eur J Clin Pharmacol       Date:  2008-10-29       Impact factor: 2.953

3.  Mass balance study of [14C] rabeprazole following oral administration in healthy subjects.

Authors:  T Setoyama; W J Drijfhout; N C van de Merbel; T J Humphries; J Hasegawa
Journal:  Int J Clin Pharmacol Ther       Date:  2006-11       Impact factor: 1.366

4.  Stereoselective metabolism of rabeprazole-thioether to rabeprazole by human liver microsomes.

Authors:  Masatomo Miura; Shigeru Satoh; Hitoshi Tada; Tomonori Habuchi; Toshio Suzuki
Journal:  Eur J Clin Pharmacol       Date:  2005-12-31       Impact factor: 2.953

5.  Pharmacokinetics and tolerability of rabeprazole sodium in subjects aged 12 to 16 years with gastroesophageal reflux disease: an open-label, single- and multiple-dose study.

Authors:  Laura James; Philip Walson; Kathleen Lomax; Richard Kao; Shanti Varughese; Josephine Reyes
Journal:  Clin Ther       Date:  2007-09       Impact factor: 3.393

Review 6.  Proton pump inhibitors--their pharmacological impact on the clinical management of acid-related disorders.

Authors:  Ulrich Klotz
Journal:  Arzneimittelforschung       Date:  2009
  6 in total

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