Literature DB >> 18958417

Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol.

Hyun-Joo Jung1, Yun Seon Song, Chang-Jin Lim, Eun-Hee Park.   

Abstract

Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.

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Year:  2008        PMID： 18958417     DOI： 10.1007/s12272-001-2106-1

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  9 in total

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