| Literature DB >> 33716724 |
Dezhi Pan1, Xue Gong2, Xiaoqin Wang1, Minhui Li1,2,3,4.
Abstract
Angiogenesis refers to the formation of new blood vessels from the endothelial cells of existing arteries, veins, and capillaries. Angiogenesis is involved in a variety of physiological and pathological processes, such as the formation of malignant and development of atherosclerosis and other diseases. In recent years, many studies have shown that the active components of food have a certain regulatory effect on angiogenesis and negligible clinical limitations. With the increasing attention being paid to medicine and food homology, exploring the effect of active food components on angiogenesis is of great significance. In this review, we discuss the source, composition, pharmacological activity, and mechanism of action of certain active components of medicinal foods in detail. These could help prevent angiogenesis-related complications or provide a basis for healthier dietary habits. This review can provide a theoretical basis for the research and development of highly efficient anti-angiogenic drugs with low toxicity.Entities:
Keywords: angiogenesis; food active components; homology of medicine and food; medicinal food; nutritional food
Year: 2021 PMID: 33716724 PMCID: PMC7944143 DOI: 10.3389/fphar.2020.594050
Source DB: PubMed Journal: Front Pharmacol ISSN: 1663-9812 Impact factor: 5.810