| Literature DB >> 18945845 |
Christian Paar1, Christina Palmetshofer, Karin Flieger, Maria Geit, Rolf Kaiser, Herbert Stekel, Jörg Berg.
Abstract
A sequencing assay for detection of mutations conferring resistance to human immunodeficiency virus type 1 (HIV-1) integrase inhibitors raltegravir and elvitegravir was developed using the automated TruGene sequencing system. The assay returned clear sequencing results for samples with >or=500 RNA copies/ml for mutation detection and HIV-1 subtyping across a spectrum of HIV-1 subtypes.Entities:
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Year: 2008 PMID: 18945845 PMCID: PMC2593279 DOI: 10.1128/JCM.01246-08
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948