| Literature DB >> 16144807 |
Niko Beerenwinkel1, Tobias Sing, Thomas Lengauer, Jörg Rahnenführer, Kirsten Roomp, Igor Savenkov, Roman Fischer, Daniel Hoffmann, Joachim Selbig, Klaus Korn, Hauke Walter, Thomas Berg, Patrick Braun, Gerd Fätkenheuer, Mark Oette, Jürgen Rockstroh, Bernd Kupfer, Rolf Kaiser, Martin Däumer.
Abstract
The development of drug resistance is a major obstacle to successful treatment of HIV infection. The extraordinary replication dynamics of HIV facilitates its escape from selective pressure exerted by the human immune system and by combination drug therapy. We have developed several computational methods whose combined use can support the design of optimal antiretroviral therapies based on viral genomic data.Entities:
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Year: 2005 PMID： 16144807 DOI： 10.1093/bioinformatics/bti654
Source DB: PubMed Journal: Bioinformatics ISSN： 1367-4803 Impact factor: 6.937