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Literature DB >> 18939833

Photoswitchable nanoparticles enable high-resolution cell imaging: PULSAR microscopy.

Dehong Hu¹, Zhiyuan Tian, Wuwei Wu, Wei Wan, Alexander D Q Li.

Abstract

Beyond-diffraction-limit optical imaging of cells will reveal biological mechanisms, cellular structures, and physiological processes in nanometer scale. Harnessing the photoswitching properties of spiropyran fluorophores, we achieved nanoresolution fluorescence imaging using photoactuated unimolecular logical switching attained reconstruction (PULSAR) microscopy. The PULSAR microscope successfully resolved nanostructures and subcellular organelles when the photoswitchable nanoparticles containing spiropyran dyes were used as fluorescent probes.

Entities: CellLine Chemical Disease Gene Species

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Year: 2008 PMID： 18939833 PMCID： PMC2651006 DOI： 10.1021/ja805948u

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

12 in total

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Authors: Ming-Qiang Zhu; Linyong Zhu; Jason J Han; Wuwei Wu; James K Hurst; Alexander D Q Li
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10. Cholesterol dictates the freedom of EGF receptors and HER2 in the plane of the membrane.

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10 in total

1. Rapid, photoactivatable turn-on fluorescent probes based on an intramolecular photoclick reaction.

Authors: Zhipeng Yu; Lok Yin Ho; Qing Lin
Journal: J Am Chem Soc Date: 2011-07-15 Impact factor: 15.419

2. Modulation and study of photoblinking behavior in dye doped silver-silica core-shell nanoparticles for localization super-resolution microscopy.

Authors: Chumki Chakraborty; S Thompson; Veronica J Lyons; Craig Snoeyink; Dimitri Pappas
Journal: Nanotechnology Date: 2019-07-29 Impact factor: 3.874

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Authors: Qingshan Wei; Alexander Wei
Journal: Chemistry Date: 2011-01-05 Impact factor: 5.236

4. Reversible photoswitching of spiropyran-conjugated semiconducting polymer dots.

Authors: Yang-Hsiang Chan; Maria Elena Gallina; Xuanjun Zhang; I-Che Wu; Yuhui Jin; Wei Sun; Daniel T Chiu
Journal: Anal Chem Date: 2012-10-22 Impact factor: 6.986

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Review 8. Switchable Fluorophores for Single-Molecule Localization Microscopy.

Authors: Honglin Li; Joshua C Vaughan
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Authors: Dehong Hu; Galya Orr
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Authors: Dojin Kim; Keunsoo Jeong; Ji Eon Kwon; Hyeonjong Park; Seokyung Lee; Sehoon Kim; Soo Young Park
Journal: Nat Commun Date: 2019-07-12 Impact factor: 14.919

10 in total