Literature DB >> 18855737

Chalcones and their potential role in inflammation.

C Kontogiorgis1, M Mantzanidou, D Hadjipavlou-Litina.   

Abstract

Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.

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Year:  2008        PMID: 18855737     DOI: 10.2174/138955708786141034

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  17 in total

1.  Methoxychalcone inhibitors of androgen receptor translocation and function.

Authors:  Yeong Sang Kim; Vineet Kumar; Sunmin Lee; Aki Iwai; Len Neckers; Sanjay V Malhotra; Jane B Trepel
Journal:  Bioorg Med Chem Lett       Date:  2012-01-21       Impact factor: 2.823

Review 2.  Chalcone: A Privileged Structure in Medicinal Chemistry.

Authors:  Chunlin Zhuang; Wen Zhang; Chunquan Sheng; Wannian Zhang; Chengguo Xing; Zhenyuan Miao
Journal:  Chem Rev       Date:  2017-05-10       Impact factor: 60.622

3.  1-Phenyl-3-(2,4,6-trimethoxy-phen-yl)prop-2-en-1-one.

Authors:  Jianzhang Wu; Li Zhang; Jing Wang; Shulin Yang; Xiaokun Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-10-23

4.  Regiospecificity of human UDP-glucuronosyltransferase isoforms in chalcone and flavanone glucuronidation determined by metal complexation and tandem mass spectrometry.

Authors:  Emily D Niemeyer; Jennifer S Brodbelt
Journal:  J Nat Prod       Date:  2013-05-29       Impact factor: 4.050

5.  The chalcone derivative (E)-1-(4-fluoro-phen-yl)-3-(4-hy-droxy-3-meth-oxy-phen-yl)prop-2-en-1-one monohydrate.

Authors:  Florastina Payton-Stewart; Subramanya Ravi Kiran Pingali; James P Donahue
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-03-23

Review 6.  Molecular targets and anticancer activity of quinoline-chalcone hybrids: literature review.

Authors:  Mamdouh F A Mohamed; Gamal El-Din A Abuo-Rahma
Journal:  RSC Adv       Date:  2020-08-21       Impact factor: 4.036

7.  TI-I-174, a Synthetic Chalcone Derivative, Suppresses Nitric Oxide Production in Murine Macrophages via Heme Oxygenase-1 Induction and Inhibition of AP-1.

Authors:  Mi Jin Kim; Taraman Kadayat; Da Eun Kim; Eung-Seok Lee; Pil-Hoon Park
Journal:  Biomol Ther (Seoul)       Date:  2014-09-30       Impact factor: 4.634

8.  Protective and antioxidant effects of a chalconoid from Pulicaria incisa on brain astrocytes.

Authors:  Anat Elmann; Alona Telerman; Hilla Erlank; Sharon Mordechay; Miriam Rindner; Rivka Ofir; Yoel Kashman
Journal:  Oxid Med Cell Longev       Date:  2013-08-28       Impact factor: 6.543

9.  Newly-synthesized chalcones-inhibition of adherence and biofilm formation of methicillin-resistant Staphylococcus aureus.

Authors:  Dragana D Bozic; Marina Milenkovic; Branka Ivkovic; Ivana Cirkovic
Journal:  Braz J Microbiol       Date:  2014-05-19       Impact factor: 2.476

10.  Antibacterial activity of three newly-synthesized chalcones & synergism with antibiotics against clinical isolates of methicillin-resistant Staphylococcus aureus.

Authors:  Dragana D Božić; Marina Milenković; Branka Ivković; Ivana Ćirković
Journal:  Indian J Med Res       Date:  2014-07       Impact factor: 2.375

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