Literature DB >> 18817395

Polymeric PARACEST agents for enhancing MRI contrast sensitivity.

Yunkou Wu1, Youfu Zhou, Olivier Ouari, Mark Woods, Piyu Zhao, Todd C Soesbe, Garry E Kiefer, A Dean Sherry.   

Abstract

Linear polymers of PARACEST agents were prepared by using classical free radical chain polymerization conditions. The Eu3+-polymers exhibited similar intermediate-to-slow water exchange and CEST characteristics as the Eu3+-monomers. This provided an avenue to lower the detection limit of these imaging agents substantially and makes them potentially useful as MRI sensors for molecular imaging.

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Year:  2008        PMID： 18817395      PMCID： PMC2723842          DOI： 10.1021/ja805775u

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  9 in total

Review 1.  Molecular imaging.

Authors:  R Weissleder; U Mahmood
Journal:  Radiology       Date:  2001-05       Impact factor: 11.105

2.  A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST).

Authors:  K M Ward; A H Aletras; R S Balaban
Journal:  J Magn Reson       Date:  2000-03       Impact factor: 2.229

3.  Gadolinium(III) Chelates as MRI Contrast Agents: Structure, Dynamics, and Applications.

Authors:  P Caravan; J J Ellison; T J McMurry; R B Lauffer
Journal:  Chem Rev       Date:  1999-09-08       Impact factor: 60.622

Review 4.  Dendrimer-based macromolecular MRI contrast agents: characteristics and application.

Authors:  Hisataka Kobayashi; Martin W Brechbiel
Journal:  Mol Imaging       Date:  2003-01       Impact factor: 4.488

Review 5.  Magnetic resonance molecular imaging with nanoparticles.

Authors:  Gregory M Lanza; Patrick M Winter; Shelton D Caruthers; Anne M Morawski; Anne H Schmieder; Katherine C Crowder; Samuel A Wickline
Journal:  J Nucl Cardiol       Date:  2004 Nov-Dec       Impact factor: 5.952

Review 6.  Paramagnetic lanthanide complexes as PARACEST agents for medical imaging.

Authors:  Mark Woods; Donald E Woessner; A Dean Sherry
Journal:  Chem Soc Rev       Date:  2006-05-10       Impact factor: 54.564

7.  The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain.

Authors:  Kenjiro Hanaoka; Angelo Josue M Lubag; Aminta Castillo-Muzquiz; Thomas Kodadek; A Dean Sherry
Journal:  Magn Reson Imaging       Date:  2008-01-30       Impact factor: 2.546

Review 8.  Dendrimer-based nanosized MRI contrast agents.

Authors:  Hisataka Kobayashi; Martin W Brechbiel
Journal:  Curr Pharm Biotechnol       Date:  2004-12       Impact factor: 2.837

9.  Pharmacokinetics of Gadomer-17, a new dendritic magnetic resonance contrast agent.

Authors:  B Misselwitz; H Schmitt-Willich; W Ebert; T Frenzel; H J Weinmann
Journal:  MAGMA       Date:  2001-05       Impact factor: 2.533
  9 in total
  30 in total

Review 1.  Alternatives to gadolinium-based metal chelates for magnetic resonance imaging.

Authors:  Subha Viswanathan; Zoltan Kovacs; Kayla N Green; S James Ratnakar; A Dean Sherry
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

2.  Towards the rational design of MRI contrast agents: δ-substitution of lanthanide(III) NB-DOTA-tetraamide chelates influences but does not control coordination geometry.

Authors:  Christiane E Carney; Anh D Tran; Jing Wang; Matthias C Schabel; A Dean Sherry; Mark Woods
Journal:  Chemistry       Date:  2011-08-11       Impact factor: 5.236

3.  Quantification of water exchange kinetics for targeted PARACEST perfluorocarbon nanoparticles.

Authors:  Kejia Cai; Garry E Kiefer; Shelton D Caruthers; Samuel A Wickline; Gregory M Lanza; Patrick M Winter
Journal:  NMR Biomed       Date:  2011-07-12       Impact factor: 4.044

Review 4.  Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics.

Authors:  Aaron Joseph L Villaraza; Ambika Bumb; Martin W Brechbiel
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

Review 5.  Advantages of paramagnetic chemical exchange saturation transfer (CEST) complexes having slow to intermediate water exchange properties as responsive MRI agents.

Authors:  Todd C Soesbe; Yunkou Wu; A Dean Sherry
Journal:  NMR Biomed       Date:  2012-10-11       Impact factor: 4.044

6.  SWIFT-CEST: a new MRI method to overcome T₂ shortening caused by PARACEST contrast agents.

Authors:  Todd C Soesbe; Osamu Togao; Masaya Takahashi; A Dean Sherry
Journal:  Magn Reson Med       Date:  2011-12-27       Impact factor: 4.668

Review 7.  Recent Advances on Luminescent Enhancement-Based Porous Silicon Biosensors.

Authors:  S N Aisyiyah Jenie; Sally E Plush; Nicolas H Voelcker
Journal:  Pharm Res       Date:  2016-02-25       Impact factor: 4.200

8.  Nanoparticle-based PARACEST agents: the quenching effect of silica nanoparticles on the CEST signal from surface-conjugated chelates.

Authors:  Osasere M Evbuomwan; Matthew E Merritt; Garry E Kiefer; A Dean Sherry
Journal:  Contrast Media Mol Imaging       Date:  2012 Jan-Feb       Impact factor: 3.161

9.  Tracking the relative in vivo pharmacokinetics of nanoparticles with PARACEST MRI.

Authors:  M Meser Ali; Byunghee Yoo; Mark D Pagel
Journal:  Mol Pharm       Date:  2009 Sep-Oct       Impact factor: 4.939

10.  Simultaneous determination of labile proton concentration and exchange rate utilizing optimal RF power: Radio frequency power (RFP) dependence of chemical exchange saturation transfer (CEST) MRI.

Authors:  Phillip Zhe Sun
Journal:  J Magn Reson       Date:  2009-11-01       Impact factor: 2.229
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