Literature DB >> 16729144

Paramagnetic lanthanide complexes as PARACEST agents for medical imaging.

Mark Woods1, Donald E Woessner, A Dean Sherry.   

Abstract

This tutorial review examines the fundamental aspects of a new class of contrast media for MRI based upon the chemical shift saturation transfer (CEST) mechanism. Several paramagnetic versions called PARACEST agents have shown utility as responsive agents for reporting physiological or metabolic information by MRI. It is shown that basic NMR exchange theory can be used to predict how parameters such as chemical shift, bound water lifetimes, and relaxation rates can be optimized to maximize the sensitivity of PARACEST agents.

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Year:  2006        PMID： 16729144      PMCID： PMC2718840          DOI： 10.1039/b509907m

Source DB:  PubMed          Journal:  Chem Soc Rev        ISSN： 0306-0012            Impact factor:   54.564


  24 in total

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Authors:  R M Henkelman; G J Stanisz; S J Graham
Journal:  NMR Biomed       Date:  2001-04       Impact factor: 4.044

2.  Novel pH-reporter MRI contrast agents.

Authors:  Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Journal:  Angew Chem Int Ed Engl       Date:  2002-11-15       Impact factor: 15.336

3.  Supramolecular adducts between poly-L-arginine and [TmIIIdotp]: a route to sensitivity-enhanced magnetic resonance imaging-chemical exchange saturation transfer agents.

Authors:  Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Journal:  Angew Chem Int Ed Engl       Date:  2003-09-29       Impact factor: 15.336

4.  A paramagnetic MRI-CEST agent responsive to lactate concentration.

Authors:  Silvio Aime; Daniela Delli Castelli; Franco Fedeli; Enzo Terreno
Journal:  J Am Chem Soc       Date:  2002-08-14       Impact factor: 15.419

5.  Renal and systemic pH imaging by contrast-enhanced MRI.

Authors:  Natarajan Raghunand; Christine Howison; A Dean Sherry; Shanrong Zhang; Robert J Gillies
Journal:  Magn Reson Med       Date:  2003-02       Impact factor: 4.668

6.  Selective sensing of zinc ions with a PARACEST contrast agent.

Authors:  Robert Trokowski; Jimin Ren; Ferenc Krisztián Kálmán; A Dean Sherry
Journal:  Angew Chem Int Ed Engl       Date:  2005-10-28       Impact factor: 15.336

7.  Highly sensitive MRI chemical exchange saturation transfer agents using liposomes.

Authors:  Silvio Aime; Daniela Delli Castelli; Enzo Terreno
Journal:  Angew Chem Int Ed Engl       Date:  2005-08-26       Impact factor: 15.336

8.  Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI.

Authors:  Donald E Woessner; Shanrong Zhang; Matthew E Merritt; A Dean Sherry
Journal:  Magn Reson Med       Date:  2005-04       Impact factor: 4.668

9.  High resolution pH(e) imaging of rat glioma using pH-dependent relaxivity.

Authors:  Maria L Garcia-Martin; Gary V Martinez; Natarajan Raghunand; A Dean Sherry; Shanrong Zhang; Robert J Gillies
Journal:  Magn Reson Med       Date:  2006-02       Impact factor: 4.668

10.  Cyclen-based phenylboronate ligands and their Eu3+ complexes for sensing glucose by MRI.

Authors:  Robert Trokowski; Shanrong Zhang; A Dean Sherry
Journal:  Bioconjug Chem       Date:  2004 Nov-Dec       Impact factor: 4.774
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  106 in total

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Authors:  Ana Christina L Opina; Yunkou Wu; Piyu Zhao; Garry Kiefer; A Dean Sherry
Journal:  Contrast Media Mol Imaging       Date:  2011 Nov-Dec       Impact factor: 3.161

Review 2.  Molecular body imaging: MR imaging, CT, and US. part I. principles.

Authors:  Moritz F Kircher; Jürgen K Willmann
Journal:  Radiology       Date:  2012-06       Impact factor: 11.105

Review 3.  Alternatives to gadolinium-based metal chelates for magnetic resonance imaging.

Authors:  Subha Viswanathan; Zoltan Kovacs; Kayla N Green; S James Ratnakar; A Dean Sherry
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

4.  MR-based molecular imaging of the brain: the next frontier.

Authors:  M E de Backer; R J A Nabuurs; M A van Buchem; L van der Weerd
Journal:  AJNR Am J Neuroradiol       Date:  2010-09-23       Impact factor: 3.825

5.  Towards the rational design of MRI contrast agents: δ-substitution of lanthanide(III) NB-DOTA-tetraamide chelates influences but does not control coordination geometry.

Authors:  Christiane E Carney; Anh D Tran; Jing Wang; Matthias C Schabel; A Dean Sherry; Mark Woods
Journal:  Chemistry       Date:  2011-08-11       Impact factor: 5.236

6.  Activation of a PARACEST agent for MRI through selective outersphere interactions with phosphate diesters.

Authors:  Ching-Hui Huang; Jacob Hammell; S James Ratnakar; A Dean Sherry; Janet R Morrow
Journal:  Inorg Chem       Date:  2010-07-05       Impact factor: 5.165

7.  The effect of regioisomerism on the coordination chemistry and CEST properties of lanthanide(III) NB-DOTA-tetraamide chelates.

Authors:  Jacqueline R Slack; Mark Woods
Journal:  J Biol Inorg Chem       Date:  2013-11-28       Impact factor: 3.358

8.  CoCEST: cobalt(II) amide-appended paraCEST MRI contrast agents.

Authors:  Sarina J Dorazio; Abiola O Olatunde; Joseph A Spernyak; Janet R Morrow
Journal:  Chem Commun (Camb)       Date:  2013-11-04       Impact factor: 6.222

9.  A QUANTUM MECHANICAL STUDY OF STRUCTURAL AND ELECTRONIC DILUTION EFFECTS IN PARAMAGNETIC CHEMICAL EXCHANGE SATURATION TRANSFER AGENTS.

Authors:  Whelton A Miller; Preston B Moore
Journal:  J Org Biomol Simul       Date:  2014

10.  Polymeric PARACEST agents for enhancing MRI contrast sensitivity.

Authors:  Yunkou Wu; Youfu Zhou; Olivier Ouari; Mark Woods; Piyu Zhao; Todd C Soesbe; Garry E Kiefer; A Dean Sherry
Journal:  J Am Chem Soc       Date:  2008-09-26       Impact factor: 15.419
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