OBJECTIVE: Intracranial subdural grid monitoring is a useful diagnostic technique for surgical localization in patients with intractable partial epilepsy. The rationale for the present study was to assess the morbidity of intracranial recordings and the surgical outcomes. METHODS: We retrospectively reviewed the clinical data for 189 unique patients undergoing 198 intracranial subdural grid monitoring sessions between 1996 and 2004 at a tertiary epilepsy center. RESULTS: The mean age of patients undergoing monitoring was 28 +/- 14 years. An average of 63 +/- 23 electrodes were inserted. The mean duration of monitoring was 8 +/- 4 days. Localization of an epileptogenic zone occurred in 156 sessions (79%) resulting in 136 resections (69%). There were 13 major complications (6.6%), including five infections and six hematomas. Three patients (1.5%) developed permanent deficits related to implantation. Sixty-two (47%) of 136 patients undergoing resection were seizure-free after resection. An additional 38 patients (28%) had a significant reduction in seizures. The mean follow-up was 51 +/- 30 months. The duration of monitoring, bone flap replacement, number of electrodes, and perioperative corticosteroids were not associated with infection or complication. CONCLUSION: Subdural grid monitoring for identification an epileptogenic focus is high yield, revealing a focus in 79% of monitoring sessions. Complications rarely result in permanent morbidity (1.5%). Surgical outcome indicated that 74% of patients experienced a favorable reduction in seizure tendency.
OBJECTIVE: Intracranial subdural grid monitoring is a useful diagnostic technique for surgical localization in patients with intractable partial epilepsy. The rationale for the present study was to assess the morbidity of intracranial recordings and the surgical outcomes. METHODS: We retrospectively reviewed the clinical data for 189 unique patients undergoing 198 intracranial subdural grid monitoring sessions between 1996 and 2004 at a tertiary epilepsy center. RESULTS: The mean age of patients undergoing monitoring was 28 +/- 14 years. An average of 63 +/- 23 electrodes were inserted. The mean duration of monitoring was 8 +/- 4 days. Localization of an epileptogenic zone occurred in 156 sessions (79%) resulting in 136 resections (69%). There were 13 major complications (6.6%), including five infections and six hematomas. Three patients (1.5%) developed permanent deficits related to implantation. Sixty-two (47%) of 136 patients undergoing resection were seizure-free after resection. An additional 38 patients (28%) had a significant reduction in seizures. The mean follow-up was 51 +/- 30 months. The duration of monitoring, bone flap replacement, number of electrodes, and perioperative corticosteroids were not associated with infection or complication. CONCLUSION: Subdural grid monitoring for identification an epileptogenic focus is high yield, revealing a focus in 79% of monitoring sessions. Complications rarely result in permanent morbidity (1.5%). Surgical outcome indicated that 74% of patients experienced a favorable reduction in seizure tendency.
Authors: Jamie J Van Gompel; Fredric B Meyer; W Richard Marsh; Kendall H Lee; Gregory A Worrell Journal: J Neurosurg Date: 2010-07 Impact factor: 5.115
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Authors: Jan Cimbalnik; Petr Klimes; Vladimir Sladky; Petr Nejedly; Pavel Jurak; Martin Pail; Robert Roman; Pavel Daniel; Hari Guragain; Benjamin Brinkmann; Milan Brazdil; Greg Worrell Journal: Clin Neurophysiol Date: 2019-08-05 Impact factor: 3.708
Authors: Jane E Huggins; Christoph Guger; Brendan Allison; Charles W Anderson; Aaron Batista; Anne-Marie A-M Brouwer; Clemens Brunner; Ricardo Chavarriaga; Melanie Fried-Oken; Aysegul Gunduz; Disha Gupta; Andrea Kübler; Robert Leeb; Fabien Lotte; Lee E Miller; Gernot Müller-Putz; Tomasz Rutkowski; Michael Tangermann; David Edward Thompson Journal: Brain Comput Interfaces (Abingdon) Date: 2014-01