OBJECTIVE: The purpose of this study was to validate the performance of a laparoscopy-based model to predict optimal cytoreduction in advanced ovarian cancer patients. STUDY DESIGN: In a consecutive prospective series of 113 advanced ovarian cancer patients, the presence of omental cake, peritoneal and diaphragmatic extensive carcinosis, mesenteric retraction, bowel and stomach infiltration, spleen and/or liver superficial metastasis were investigated by laparoscopy. By summing the scores relative to all parameters, a laparoscopic assessment for each patient (total predictive index value = PIV) has been calculated. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy have been calculated for each PIV. RESULTS: The overall accuracy rate of the laparoscopic procedure ranged between 77.3 and 100%. At a PIV >/= 8 the probability of optimally resecting the disease at laparotomy is equal to 0, and the rate of unnecessary exploratory laparotomy is 40.5%. CONCLUSION: The proposed laparoscopic model appears a reliable and flexible tool to predict optimal cytoreduction in advanced ovarian cancer.
OBJECTIVE: The purpose of this study was to validate the performance of a laparoscopy-based model to predict optimal cytoreduction in advanced ovarian cancerpatients. STUDY DESIGN: In a consecutive prospective series of 113 advanced ovarian cancerpatients, the presence of omental cake, peritoneal and diaphragmatic extensive carcinosis, mesenteric retraction, bowel and stomach infiltration, spleen and/or liver superficial metastasis were investigated by laparoscopy. By summing the scores relative to all parameters, a laparoscopic assessment for each patient (total predictive index value = PIV) has been calculated. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy have been calculated for each PIV. RESULTS: The overall accuracy rate of the laparoscopic procedure ranged between 77.3 and 100%. At a PIV >/= 8 the probability of optimally resecting the disease at laparotomy is equal to 0, and the rate of unnecessary exploratory laparotomy is 40.5%. CONCLUSION: The proposed laparoscopic model appears a reliable and flexible tool to predict optimal cytoreduction in advanced ovarian cancer.
Authors: Natalia Rodriguez Gómez-Hidalgo; Bertha Alejandra Martinez-Cannon; Alpa M Nick; Karen H Lu; Anil K Sood; Robert L Coleman; Pedro T Ramirez Journal: Gynecol Oncol Date: 2015-03-28 Impact factor: 5.482
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Authors: Emma L Barber; Stacie B Dusetzina; Karyn B Stitzenberg; Emma C Rossi; Paola A Gehrig; John F Boggess; Joanne M Garrett Journal: Gynecol Oncol Date: 2017-03-31 Impact factor: 5.482
Authors: Robert L Dood; Nicole D Fleming; Robert L Coleman; Shannon N Westin; Olivia D Lara; Christopher J LaFargue; Jinsong Liu; Anil K Sood Journal: Int J Gynecol Cancer Date: 2018-10 Impact factor: 3.437
Authors: Mercedes Espada; Jose R Garcia-Flores; Mar Jimenez; Elena Alvarez-Moreno; Mar De Haro; Lucia Gonzalez-Cortijo; Gines Hernandez-Cortes; Vicente Martinez-Vega; Ricardo Sainz De La Cuesta Journal: Eur Radiol Date: 2013-04-19 Impact factor: 5.315
Authors: G Ferrandina; G Sallustio; A Fagotti; G Vizzielli; A Paglia; E Cucci; A Margariti; L Aquilani; G Garganese; G Scambia Journal: Br J Cancer Date: 2009-09-08 Impact factor: 7.640