Literature DB >> 18794385

Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans.

Nathan P Wiederhold1, Jodi L Grabinski, Guillermo Garcia-Effron, David S Perlin, Samuel A Lee.   

Abstract

Pyrosequencing was compared to Sanger dideoxy sequencing to detect mutations in FKS1 responsible for reduced echinocandin susceptibility in Candida albicans. These methods were in complete agreement for 10 of 12 clinical isolates with elevated echinocandin MICs, supporting the potential feasibility of pyrosequencing to detect mutations within diploid fungi.

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Year:  2008        PMID： 18794385      PMCID： PMC2573102          DOI： 10.1128/AAC.00959-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

1.  Detection of Aspergillus fumigatus and a mutation that confers reduced susceptibility to itraconazole and posaconazole by real-time PCR and pyrosequencing.

Authors:  Jason P Trama; Eli Mordechai; Martin E Adelson
Journal:  J Clin Microbiol       Date:  2005-02       Impact factor: 5.948

Review 2.  Pyrosequencing: history, biochemistry and future.

Authors:  Afshin Ahmadian; Maria Ehn; Sophia Hober
Journal:  Clin Chim Acta       Date:  2005-09-13       Impact factor: 3.786

3.  Emergence of disseminated candidiasis caused by Candida krusei during treatment with caspofungin: case report and review of literature.

Authors:  René Pelletier; Isabelle Alarie; Réal Lagacé; Thomas J Walsh
Journal:  Med Mycol       Date:  2005-09       Impact factor: 4.076

4.  Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.

Authors:  S Park; R Kelly; J Nielsen Kahn; J Robles; M-J Hsu; E Register; W Li; V Vyas; H Fan; G Abruzzo; A Flattery; C Gill; G Chrebet; S A Parent; M Kurtz; H Teppler; C M Douglas; D S Perlin
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

5.  Multiechinocandin- and multiazole-resistant Candida parapsilosis isolates serially obtained during therapy for prosthetic valve endocarditis.

Authors:  Varsha Moudgal; Tania Little; Dina Boikov; Jose A Vazquez
Journal:  Antimicrob Agents Chemother       Date:  2005-02       Impact factor: 5.191

6.  In vivo efficacy of anidulafungin and caspofungin against Candida glabrata and association with in vitro potency in the presence of sera.

Authors:  Nathan P Wiederhold; Laura K Najvar; Rosie Bocanegra; Destiny Molina; Marcos Olivo; John R Graybill
Journal:  Antimicrob Agents Chemother       Date:  2007-02-16       Impact factor: 5.191

7.  Genotypic and allelic frequencies of SULT1A1 polymorphisms in women receiving adjuvant tamoxifen therapy.

Authors:  J L Grabinski; L S Smith; G B Chisholm; R Drengler; G I Rodriguez; A S Lang; S P Kalter; A M Garner; L M Fichtel; J Hollsten; B H Pollock; J G Kuhn
Journal:  Breast Cancer Res Treat       Date:  2006-01       Impact factor: 4.872

8.  Pyrosequencing for detection of lamivudine-resistant hepatitis B virus.

Authors:  Anna Lindström; Jacob Odeberg; Jan Albert
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948

9.  Comparison of caspofungin and amphotericin B for invasive candidiasis.

Authors:  Jorge Mora-Duarte; Robert Betts; Coleman Rotstein; Arnaldo Lopes Colombo; Luis Thompson-Moya; Juanita Smietana; Robert Lupinacci; Carole Sable; Nicholas Kartsonis; John Perfect
Journal:  N Engl J Med       Date:  2002-12-19       Impact factor: 91.245

10.  Amphotericin B and caspofungin resistance in Candida glabrata isolates recovered from a critically ill patient.

Authors:  Mikkel Krogh-Madsen; Maiken Cavling Arendrup; Lars Heslet; Jenny Dahl Knudsen
Journal:  Clin Infect Dis       Date:  2006-02-27       Impact factor: 9.079
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  31 in total

1.  Quick Detection of FKS1 Mutations Responsible for Clinical Echinocandin Resistance in Candida albicans.

Authors:  Catiana Dudiuk; Soledad Gamarra; Cristina Jimenez-Ortigosa; Florencia Leonardelli; Daiana Macedo; David S Perlin; Guillermo Garcia-Effron
Journal:  J Clin Microbiol       Date:  2015-04-15       Impact factor: 5.948

2.  In vitro assessment of the antifungal and paradoxical activity of different echinocandins against Candida tropicalis biofilms.

Authors:  Tsun Sheng N Ku; Stella M Bernardo; Samuel A Lee
Journal:  J Med Microbiol       Date:  2011-06-23       Impact factor: 2.472

Review 3.  Echinocandin resistance, susceptibility testing and prophylaxis: implications for patient management.

Authors:  David S Perlin
Journal:  Drugs       Date:  2014-09       Impact factor: 9.546

Review 4.  Antifungal therapy with an emphasis on biofilms.

Authors:  Christopher G Pierce; Anand Srinivasan; Priya Uppuluri; Anand K Ramasubramanian; José L López-Ribot
Journal:  Curr Opin Pharmacol       Date:  2013-09-04       Impact factor: 5.547

5.  In vitro analyses of the effects of heparin and parabens on Candida albicans biofilms and planktonic cells.

Authors:  Marisa H Miceli; Stella M Bernardo; T S Neil Ku; Carla Walraven; Samuel A Lee
Journal:  Antimicrob Agents Chemother       Date:  2011-10-10       Impact factor: 5.191

Review 6.  Resistance of Candida spp. to antifungal drugs in the ICU: where are we now?

Authors:  Danièle Maubon; Cécile Garnaud; Thierry Calandra; Dominique Sanglard; Muriel Cornet
Journal:  Intensive Care Med       Date:  2014-08-05       Impact factor: 17.440

7.  Low prevalence of fks1 hot spot 1 mutations in a worldwide collection of Candida strains.

Authors:  Mariana Castanheira; Leah N Woosley; Daniel J Diekema; Shawn A Messer; Ronald N Jones; Michael A Pfaller
Journal:  Antimicrob Agents Chemother       Date:  2010-04-05       Impact factor: 5.191

8.  Increasing echinocandin resistance in Candida glabrata: clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations.

Authors:  Barbara D Alexander; Melissa D Johnson; Christopher D Pfeiffer; Cristina Jiménez-Ortigosa; Jelena Catania; Rachel Booker; Mariana Castanheira; Shawn A Messer; David S Perlin; Michael A Pfaller
Journal:  Clin Infect Dis       Date:  2013-03-13       Impact factor: 9.079

9.  Paradoxical antifungal activity and structural observations in biofilms formed by echinocandin-resistant Candida albicans clinical isolates.

Authors:  Carla J Walraven; Stella M Bernardo; Nathan P Wiederhold; Samuel A Lee
Journal:  Med Mycol       Date:  2013-12-22       Impact factor: 4.076

10.  Wild-type MIC distributions and epidemiological cutoff values for the echinocandins and Candida spp.

Authors:  M A Pfaller; L Boyken; R J Hollis; J Kroeger; S A Messer; S Tendolkar; R N Jones; J Turnidge; D J Diekema
Journal:  J Clin Microbiol       Date:  2009-11-18       Impact factor: 5.948
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